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陈晓

性别:男
职称:副教授
单位:医学院

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陈晓

发表论文

1Fos Promotes Early Stage   Teno-Lineage Differentiation of Tendon Stem/Progenitor Cells in Tendon.
           Chen J(#), Zhang E(#), Zhang W, Liu Z, Lu P, Zhu T, Yin Z, Backman LJ, Liu   H,
Chen X(*) and Ouyang   H(*).
           
   
Stem Cells Transl Med.   2017 Nov;6(11):2009-2019. doi: 10.1002/sctm.15-0146. Epub 2017 Oct 10. (共同通讯)
2An Epigenetic   Bioactive Composite Scaffold with Well-aligned Nanofibers for Functional   Tendon Tissue Engineering.
           Zhang C(#), Wang X(#), Zhang E, Yang L, Yuan H, Tu W, Zhang H, Yin Z, Shen   W,
Chen X(*), Zhang Y(*) and   Ouyang H(*)
           
   
Acta Biomater. 2017   Sep 26. pii: S1742-7061(17)30608-6. doi: 10.1016/j.actbio.2017.09.036. [Epub   ahead of print](共同通讯)
3Biomimetic   tendon extracellular matrix composite gradient scaffold enhances   ligament-to-bone junction reconstruction.
           Liu H(#), Yang L(#), Zhang E, Zhang R, Cai D, Zhu S, Ran J, Bunpetch V, Cai   Y, Heng BC, Hu Y, Dai X,
Chen X(*) and Ouyang H(*)
           
   
 Acta   Biomater. 2017. 56: 129-140. (共同通讯)
4Single-cell   analysis reveals a nestin+tendon stem/progenitor cell population with strong   tenogenic potentiality.
           Yin Zi(#); Hu Jia-jie(#); Yang Long; Zheng Ze-Feng; An Cheng-rui; Wu   Bing-bing; Zhang Can; Shen Wei-Liang; Liu Huan-huan; Chen Jia-lin; Heng Boon   Chin; Guo Guo-ji;
Chen Xiao(*)and   Ouyang Hong-Wei(*).
           
   
Science Advances.   2016 Nov 18;2(11):e1600874. doi: 10.1126/sciadv.1600874. (Science子刊, 共同通讯).
5Pharmacological   Regulation of In Situ Tissue Stem Cells Differentiation for Soft Tissue   Calcification Treatment
           
           
     Hu JiaJie(#),   Yin Zi(#),  Shen Weiliang,  Xie Yubin,    Zhu Ting,  Lu Ping,  Cai Youzhi, Kong Minjian,  Heng Boon Chin,  Zhou Yiting,  Chen Weishan,  Chen Xiao(*) and   Ouyang Hongwei(*)
           
   
STEM CELLS, 2016.34   (4): 1083-1096, DOI: 10.1002/stem.2306    (IF= 5.902, 共同通讯).
6Nanoparticle   delivery of stable miR-199a-5p agomir improves the osteogenesis of human   mesenchymal stem cells via the HIF1a pathway
           
           
    Chen Xiao(#),Gu Shen(#),Chen   Bifeng,Shen Weiliang,Yin Zi,Xu Guowei,Hu Jiajie,Zhu Ting,Li Gang,Wan   Chao,Ouyang Hongwei,Lee Tin Lap(*),Chan Wai Yee(*)
           
   
BIOMATERIALS, 2015.53   239-250, DOI: 10.1016/j.biomaterials.2015.02.071
7Electrospun   scaffolds for multiple tissues regeneration in vivo through topography   dependent induction of lineage specific differentiation
           
           Yin Zi(#)
Chen Xiao(#),Song Haixing,Hu Jiajie,Tang Qiaomei,Zhu Ting,Shen   Weiliang,Chen Jialin,Liu Huanhuan,Heng BC,Ouyang Hongwei(*)
           
   
BIOMATERIALS, 2015.44   173-185, DOI: 10.1016/j.biomaterials.2014.12.027 (IF= 8. 387, 共同一作).
8Mohawk Promotes   the Tenogenesis of Mesenchymal Stem Cells Through Activation of the TGF beta   Signaling Pathway
           
           
     Liu Huanhuan, Zhang Can, Zhu Shouan,   Lu Ping, Zhu Ting, Gong Xiaonan, Hu Jiajie, Yin Zi, Chen   Xiao(*), Ouyang Hongwei(*).
           
   
STEM CELLS, 2015.33   (2): 443-455, DOI: 10.1002/stem.1866
9Scleraxis-Overexpressed   Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells for Tendon Tissue   Engineering with Knitted Silk-Collagen Scaffold
           
    Chen X(#), Yin Z(#), Chen   JL, Liu HH, Shen WL, Fang Z, Zhu T, Ji JF Ouyang HW and Zou XH(*)
           
   
Tissue Eng Part A,   2014 Jun;20(11-12):1583-92. doi: 10.1089/ten.TEA.2012.0656. Epub 2014 Feb 6.
10Transplantation   of Fetal Instead of Adult Fibroblasts Reduces the Probability of Ectopic   Ossification During Tendon Repair
           
           7. Fang Z, Zhu T, Shen W, Tang Q, Chen J, Zi Y, Ji JF, Heng BC, Ouyang HW
(*), Chen X(*)
           
TISSUE ENGINEERING PART A, 2014.20 (13-14): 1815-1826, DOI: 10.1089/ten.tea.2013.0296   (IF= 3.892,医学部top期刊)
11Fetal and adult   fibroblasts display intrinsic differences in tendon tissue engineering and   regeneration
           
           Tang QM, Chen JL, Shen WL, Yin Z, Liu HH, Fang Z, Heng BC, Ouyang HW* and
Chen X*
           
SCIENTIFIC REPORTS,   2014.4 , DOI: 10.1038/srep05515  (IF =5.228,Nature旗下网站highlight)
12Force and   scleraxis synergistically promote the commitment of human ES cells derived   MSCs to tenocytes
           
           
     Chen X(#), Yin Z(#), Chen JL, Shen WL, Liu HH, Tang QM, Fang Z, Lu LR,   Ji J*, Ouyang HW*.
           
   
SCIENTIFIC REPORTS,   2012.2 , DOI: 10.1038/srep00977
13Stepwise   Differentiation of Human Embryonic Stem Cells Promotes Tendon Regeneration by   Secreting Fetal Tendon Matrix and Differentiation Factors
           
           
     Chen X, Song XH, Yin Z, Zou XH, Wang LL, Hu H, Cao T, Zheng M, and   Ouyang HW*
           
   
STEM CELLS, 2009.27   (6): 1276-1287, DOI: 10.1002/stem.61
14Ligament   regeneration using a knitted silk scaffold combined with collagen   matrix
           
           Chen X, Qi YY, Wang LL, Yin Z, Yin GL, Zou XH, and Ouyang HW*
           
    BIOMATERIALS, 2008.29 (27):   3683-3692, DOI: 10.1016/j.biomaterials.2008.05.017
15Crucial   transcription factors in tendon development and differentiation: their   potential for tendon regeneration
           
           Liu Huanhuan(#)
,Zhu Shouan(#),Zhang Can,Lu Ping,Hu   Jiajie,Yin Zi,Ma Yue,Chen Xiao(*),Ouyang Hongwei(*)
           
   
CELL AND TISSUE RESEARCH, 2014.356 (2): 287-298, DOI: 10.1007/s00441-014-1834-8  (IF= 2.948, 共同通讯)
16Long-term   effects of knitted silk-collagen sponge scaffold on anterior cruciate   ligament reconstruction and osteoarthritis prevention
           
           Shen W
(#), Chen X(#), Hu Y, Yin Z, Zhu T, Hu J, Chen J, Zheng Z, Zhang W, Ran J,   Heng BC, Ji J, Chen W and Ouyang HW
           
   
BIOMATERIALS, 2014.35   (28): 8154-8163, DOI: 10.1016/j.biomaterials.2014.06.019  (IF= 8. 387, 共同一作).
17The effect of   decellularized matrices on human tendon stem/progenitor cell differentiation   and tendon repair
           
           Yin Z
(#), Chen X(#), Zhu T, Hu JJ, Song HX, Jiang LY, Heng BC, Ji JF and Ouyang   HW*
           
   
ACTA BIOMATERIALIA,   2013.9 (12): 9317-9329, DOI: 10.1016/j.actbio.2013.07.022  (IF=6.008, 共同一作).
18The regulation   of tendon stem cell differentiation by the alignment of nanofibers
           .
           Yin Z
(#), Chen X(#), Chen JL, Shen WL, Hieu Nguyen TM, Gao L, and Ouyang HW
           
   
BIOMATERIALS, 2010.31   (8): 2163-2175, DOI: 10.1016/j.biomaterials.2009.11.083
           (IF= 8. 387, 共同一作).
19Stem cells for   tendon tissue engineering and regeneration
           
           
     Yin Z(#), Chen X(#), Chen JL, and Ouyang   HW
           
   
EXPERT OPINION ON BIOLOGICAL THERAPY, 2010.10 (5): 689-700, DOI: 10.1517/14712591003769824  (IF= 3.438, 共同一作)
20Tendon tissue   engineering with mesenchymal stem cells and biografts: An option for large   tendon defects?
           
    Chen X, Zou XH, Yin Gl, and   Ouyang HW,
           
   
Frontiers in Bioscience,   2009. S1(1): 23-32.
21Stepwise   Differentiation of Mesenchymal Stem Cells Augments Tendon-Like Tissue   Formation and Defect Repair In Vivo
           
           Yin Z, Guo J, Wu TY,
Chen X,   Xu LL, Lin SE, Sun YX, Chan KM, Ouyang H and Li G(*)
           
   
STEM CELLS TRANSLATIONAL MEDICINE, 2016.5 (8): 1106-1116, DOI: 10.5966/sctm.2015-0215
22Well-aligned   chitosan-based ultrafine fibers committed teno-lineage differentiation of   human induced pluripotent stem cells for Achilles tendon regeneration
           
           Zhang Can (#) ,Yuan Huihua(#) ,Liu Huanhuan,
Chen Xiao,Lu Ping,Zhu Ting,Yang Long,Yin Zi,Heng Boon CHin,Zhang   Yanzhong(*),Ouyang Hongwei(*)
           
   
BIOMATERIALS, 2015.53   716-730, DOI: 10.1016/j.biomaterials.2015.02.051
23Characterization   and comparison of post-natal rat Achilles tendon-derived stem cells at   different development stages.
           Chen J, Zhang W, Liu Z, Zhu T, Shen W, Ran J, Tang Q, Gong X, Backman LJ,
Chen X, Chen X, Wen F and Ouyang   H.
           
   
 Sci Rep. 2016. 6: 22946
24Intra-Articular   Injection of Human Meniscus Stem/Progenitor Cells Promotes Meniscus   Regeneration and Ameliorates Osteoarthritis Through Stromal Cell-Derived   Factor-1/CXCR4-Mediated Homing
           
           Shen W, Chen J, Zhu T, Chen L, Zhang W, Fang Z, Heng BC, Yin Z,
Chen X, Ji J, Chen W, Ouyang   HW
           
   
STEM CELLS TRANSLATIONAL MEDICINE, 2014.3 (3): 387-394, DOI: 10.5966/sctm.2012-0170
25The Promotion of   Bone Regeneration by Nanofibrous Hydroxyapatite/Chitosan Scaffolds by Effects   on Integrin-BMP/Smad Signaling Pathway in BMSCs.
           5. Liu HH, Peng HJ, Wu Y , Zhang C, Cai YZ, Xu GW, Li Q,
Chen X , Ji JF, Zhang YZ(*), OuYang   HW(*),
           
   
Biomaterials,2013,34(18):4404-17
26Allogenous   Tendon Stem/Progenitor Cells in Silk Scaffold for Functional Shoulder   Repair
           
           Shen W, Chen J, Yin Z,
Chen X,   Liu H, Heng BC, Chen W., and Ouyang HW
           
   
CELL TRANSPLANTATION,   2012.21 (5): 943-958, DOI: 10.3727/096368911X627453
27Osteoarthritis   Prevention Through Meniscal Regeneration Induced by Intra-Articular Injection   of Meniscus Stem Cells
           
           Shen, Weiliang; Chen, Jialin; Zhu, Ting; Yin, Zi;
Chen,   Xiao; Chen, Longkun; Fang, Zhi; Heng, Boon Chin;   Ji, Junfeng; Chen, Weishan; Ouyang, Hong-Wei
           
           
   
STEM CELLS AND DEVELOPMENT, 2013.22 (14): 2071-2082, DOI: 10.1089/scd.2012.0563
28LIF-dependent   primitive neural stem cells derived from mouse ES cells represent a   reversible stage of neural commitment.
           8. Tsang WH, Wang B, Wong WK, Shi S,
Chen X, He X, Gu S, Hu J, Wang C, Liu PC, Lu G, Chen X, Zhao H, Poon   WS, Chan WY and Feng B.
           
   
Stem Cell Res,   2013,11(3):1091-102.
29Electrospun   biomimetic scaffold of hydroxyapatite/chitosan supports enhanced osteogenic   differentiation of mMSCs
           
           Peng, Hongju; Yin, Zi; Liu, Huanhuan;
Chen, Xiao; Feng, Bei; Yuan, Huihua; Su, Bo; Ouyang, Hongwei; Zhang,   Yanzhong
           
           
   
NANOTECHNOLOGY,   2012.23 (48): , DOI: 10.1088/0957-4484/23/48/485102
30Tissue   Engineering for Soft Tissue Regeneration.
           Zou XH, Jiang YZ, Chen JL,
Chen X, Hong Wei Ouyang.
           Science.(Suppl Regenerative medicine in China). 2012, May, P33-34.
31The effect of   incorporation of exogenous stromal cell-derived factor-1 alpha within a   knitted silk-collagen sponge scaffold on tendon regeneration
           
           Shen, Weiliang;
Chen, Xiao;   Chen, Jialin; Yin, Zi;   Heng, Boon Chin; Chen, Weishan; Ouyang, Hong-Wei
           
           
   
BIOMATERIALS, 2010.31   (28): 7239-7249, DOI: 10.1016/j.biomaterials.2010.05.040
32Efficacy of   hESC-MSCs in knitted silk-collagen scaffold for tendon tissue engineering and   their roles
           
           Chen, Jia Lin; Yin, Zi; Shen, Wei Liang;
Chen, Xiao; Heng, Boon Chin; Zou, Xiao Hui; Ouyang, Hong Wei
           
           
   
BIOMATERIALS, 2010.31   (36): 9438-9451, DOI: 10.1016/j.biomaterials.2010.08.011
33Mesenchymal stem   cell seeded knitted silk sling for the treatment of stress urinary   incontinence
           
           Zou, Xiao Hui; Zhi, Yun Long;
Chen, Xiao; Jin, Hang Mei; Wang, Lin Lin; Jiang, Yang Zi; Yin, Zi;   Ouyang, Hong Wei
           
           
   
BIOMATERIALS, 2010.31   (18): 4872-4879, DOI: 10.1016/j.biomaterials.2010.02.056
34Local  Delivery of Autologous Platelet in Collagen   Matrix Synergistically Stimulated In-situ Articular Cartilage Repair.
           Qi YY,
Chen X, Wang LL,   Jiang YZ, Hieu NTM, and Ouyang HW,
           
   
Cell Transplantation,   2009. 18(10): 1161-1169
35Novel strategy   incorporated the power of mesenchymal stem cells to allografts for segmental   bone tissue engineering.
           Zou XH, Cai HX, Yin Z,
Chen X,   Hu H, and Ouyang HW, 
           
Cell transplantation,   2009. 18(4): 433-441.
36Intratendon   Delivery of Leukocyte-Poor Platelet-Rich Plasma Improves Healing Compared   With Leukocyte-Rich Platelet-Rich Plasma in a Rabbit Achilles Tendinopathy   Model. Ruijian Yan, Yanjia Gu, Jisheng Ran, Yejun Hu, Zefeng Zheng, Mengfeng   Zeng,  Boon Chin Heng, Xiao Chen, Zi Yin, Weishan Chen,   Weiliang Shen, Hongwei Ouyang.
           
   
The American Journal of Sports Medicine.2017 July 1; Volume: 45 issue: 8, page(s): 1909-1920
37Ectopic tissue   engineered ligament with silk collagen scaffold for ACL regeneration: A   preliminary study.Ran J, Hu Y, Le H, Chen Y, Zheng Z, Chen   X, Yin Z, Yan R, Jin Z, Tang C, Huang J, Gu Y, Xu   L, Qian S, Zhang W, Heng BC, Dominique P, Chen W, Wu L, Shen W, Ouyang   H.
           
   
Acta Biomater. 2017   Apr 15;53:307-317. doi: 10.1016/j.actbio.2017.02.027. Epub 2017 Feb 16
38Alignment of   collagen fiber in knitted silk scaffold for functional massive rotator cuff   repair. Acta Biomater.
           Zheng Z, Ran J, Chen W, Hu Y, Zhu T,
Chen X, Yin Z, Heng BC, Feng G, Le H, Tang C, Huang J, Chen Y, Zhou   Y, Dominique P, Shen W, Ouyang HW.

                 Acta   Biomater.

2017 Mar 15;51:317-329. doi: 10.1016/j.actbio.2017.01.041.