Profile

Employment

  •  Zhejiang University, Hangzhou, Zhejiang, China

    • Associate professor, Department of Basic Medicine, School of Medicine, 2015.12-Present.

    • Lecturer, Department of Basic Medicine, School of Medicine, 2015.9-2015.12.

Education and professonal training

  • Baylor College of Medicine (BCM), Houston, Texas, US

    • Postdoc associate, Huffington Center on Aging, 2014.10-2015.7.

    • Ph.D., Department of Molecular and Human Genetics, Huffington Center on Aging, 2009.8-2014.10.

  • Zhejiang University, Hangzhou, China

    • M.S. in Zoology, College of Life Sciences, the Key Laboratory of Conservation Genetics and Reproductive Biology for Endangered Wild Animals, 2007.9-2009.6.

    • B.S. in Biological Sciences, College of Life Sciences, Chukechen Honor College, 2003.9-2007.6. 

Publications

  • Lian H#, Litvinchuk A#, Chang A, Aithmitti N, Jankowsky JL and Zheng H, Astrocyte-Microglia Crosstalk through Complement Activation Modulates Amyloid Pathology in Mouse Models of Alzheimer's Disease, Journal of Neuroscience (IF 6.344), 2016, 36(2):577-589. (#Co-first author)

  • Lian H and Zheng H, Signaling Pathways Regulating Neuron-Glia Interaction and Their Implications in Alzheimer's Disease, Journal of Neurochemistry (IF 4.281), 2016, 136(3)475-491.

  • Lian H, Yang L, Cole A, Sun L, Chang A, Fowler S, Shim DJ, Rodriguez-Rivera J, Taglialatela G, Jankowsky JL, Lu HC and Zheng H, NFκB-activated astroglial release of complement C3 compromises neuronal morphology and function associated with Alzheimer’s disease, Neuron (IF 15.982), 2015, 85(1):101-115.

  • Lian H#, Shim DJ#, Gaddam SS, Rodriguez-Rivera J, Bitner BR, Pautler RG, Robertson CS and Zheng H. IκBα deficiency in brain leads to elevated basal neuroinflammation and attenuated response following traumatic brain injury: Implications for functional recovery, Molecular Neurodegeneration (IF 5.29), 2012, 7:47.(#Co-first author)

  • Lian H, Yu JQ, Ge YF and Fang SG, Nine novel microsatellite markers for the hog deer (Axis porcinus), Conservation Genetics (IF 1.846), 2009, 10(3):681-683. 


Research work

The neuron-glia interaction and signal transduction between neurons are essential for the homeostasis and physiological function of the central nervous system. Disruption of these functions is involved in many neurological and neuropsychiatric diseases. My research interests are on the signaling pathways connecting neuron and glia as well as neural circuits through different brain regions and how they integrate and regulate cognition, emotion, and behavior.

Contact

Phone:86-571-88206092
E-mail:honglian@zju.edu.cn