Profile

2010-current   Instructor, Zhejiang University

2008-2010     Posdoc in Preventive Veterinary Medicine, Zhejiang University, China

2002-2007     Ph.D. in Microbiology, Zhejiang University, China.

1998-2002     B.V.S. in Veterinary Medicine, Zhejiang University, China.

Research work

Infection bursal disease virus (IBDV), a member of the Birnaviridae family, is a major pathogen of chicken which damaging the precursors of antibody-producing B lymphocytes. So far, little is known about the replication mechanism and pathogenesis of IBDV infection, especially the molecular functions of serine protease VP4. My doctoral research in microbiology focuses on differential proteomes of host cells infected with avibirnavirus using two-dimensional electrophoresis and MALDI-TOF/TOF mass spectrometry to characterize the cellular response to viral infection (Molecular & Cellular Proteomics, 2008, 7: 613-625). In addition, I prepared and identified the monoclonal antibody of RNA-dependent RNA polymerase for avibirnavirus using the recombinant prokaryotic proteins as antigens, and analyzed its subcellular location (DNA and Cell Biology, 2006, 25: 646-653). My postdoctoral studies focus on the aggregation mechanism and phosphorylation analysis of serine protease VP4 of avibirnavirus.

Contact

Phone:86-571-86971607
E-mail:zhengxiaojuan@zju.edu.cn