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杨帆

性别:男
职称:
单位:医学院
电子信箱:0017027@zju.edu.cn

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杨帆 浙江大学
24
Sep

发表论文

1. F. Yang and J. Zheng (2017) Understand spiciness: mechanism of TRPV1 channel activation by capsaicin, Protein & Cell, doi:10.1007/s13238-016-0353-7


2. Ma. L§, F. Yang§, S. Vu and J. Zheng (2016) Exploring functional roles of TRPV1 intracellular domains with unstructured peptide-insertion screening, Scientific Reports, 6: 33827. (§ equal contribution)


3. F. Yang§, S. Vu§, Yarov-Yarovoy and J. Zheng (2016) Rational design and validation of a vanilloid-sensitive TRPV2 ion channel, Proceedings of the National Academy of Sciences, 113(26): E3657-66. (§ equal contribution) **Recommended by Faculty 1000


4. F. Yang§, X. Xiao§, W. Cheng, W. Yang, PL. Yu, ZZ. Song, V. Yarov-Yarovoy and J. Zheng (2015) Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel, Nature Chemical Biology, 11(7): 518-524. (§ equal contribution)


5. SL. Yang§, F. Yang§, NN. Wei§, J. Hong, BW. Li, L. Luo, MQ. Rong, V. Yarov-Yarovoy, J. Zheng, KW. Wang and R. Lai (2015) A pain-inducing centipede toxin targets the heat activation machinery of nociceptor TRPV1, Nature Communications, 6:8279. (§ equal contribution)


6. YQ. Tang, JH. Zhou, F. Yang, J. Zheng and KW. Wang (2014) The tetramerization domain potentiates Kv4 channel function by suppressing closed-state inactivation, Biophysical Journal, 107(5): 1090-1104.


7. F. Yang and J. Zheng (2014) High temperature sensitivity is intrinsic to voltage-gated potassium channels, eLife, 3: e03255.


8. X. Cao, L. Ma, F. Yang, KW. Wang and J. Zheng (2014) Divalent cations potentiate TRPV1 channel by lowering the heat activation threshold, Journal of General Physiology, 143(1): 75-90.


9. F. Yang§, L. Ma§, X. Cao§, KW. Wang and J. Zheng (2014) Divalent cations activate TRPV1 through promoting conformational change of the extracellular region, Journal of General Physiology, 143(1): 91-103. (§ equal contribution)


10. Ma, L., F. Yang, and J. Zheng (2014) Application of fluorescence resonance energy transfer in studies of biomolecules, Journal of Molecular Structure, 1077: 87-100.


11. L. Lei, F. Yang, DJ. Shi, YQ. Tang, J. Zheng and KW. Wang (2013) A TRPV4 channel C-terminal folding recognition domain critical for trafficking and function, Journal of Biological Chemistry, 288(15): 10427-10439.


12. X. Cao, F. Yang, J. Zheng and KW. Wang (2012) Intracellular proton-mediated activation of TRPV3 channels accounts for exfoliation effect of alpha hydroxyl acids on keratinocytes, Journal of Biological Chemistry, 287(31): 25905-25916.


13. Y. Cui, F. Yang, X. Cao, V. Yarov-Yarovoy, KW. Wang and J. Zheng (2012) Selective disruption of high-sensitivity heat activation but not capsaicin activation of TRPV1 channels by pore turret mutations, Journal of General Physiology, 139(4): 273-283. **Featured on the Cover.


14. W. Cheng§, F. Yang§, S. Liu, C. K. Colton, CB. Wang, Y. Cui, X. Cao, M.X. Zhu, CS. Sun, KW. Wang and J. Zheng (2012) Heteromeric heat-sensitive TRP channels exhibit distinct temperature and chemical response, Journal of Biological Chemistry, 287(10): 7279-7288. (§ equal contribution)


15. F. Zhang, S. Liu, F. Yang, J. Zheng and KW. Wang (2011) Identification of a tetrameric assembly domain in the c-terminus of heat-activated TRPV1 channels, Journal of Biological Chemistry, 286(17): 15308-15316.


16. F. Yang, Y. Cui, KW. Wang and J. Zheng (2010) Thermosensitive TRP channel pore turret is part of the temperature activation pathway, Proceedings of the National Academy of Sciences, 107(15): 7083-8 **Highlighted by Cell 141(3):377 and Faculty 1000


17. SS. Liang, F. Yang, C. Zhou, Y. Wang, S. Li, C. K. Sun, J. L. Puglisi, D. Bers, CS. Sun, and J. Zheng (2009) Temperature-dependent activation of neurons by continuous near-infrared laser, Cell Biochemistry and Biophysics, 53(1): 33–42


18. W. Cheng, F. Yang, C. L. Takanishi, and J. Zheng (2007) Thermosensitive TRPV channel subunits co-assemble into heteromeric channels with intermediate conductance and gating properties, Journal of General Physiology, 129(3): 191-207 **Featured on the Cover.


19. MZ. Wang, S. Qiu, YL. Hua, F. Yang, Y. Shen, JH. Luo (2005) Optimization of three-cube FRET assay and application in the analysis of subunit assembling of iGluR receptors in living cells, Acta Anatomica Sinica, 36(4): 447-451


20. S. Qiu, YL. Hua, F. Yang, YZ. Chen, and JH. Luo (2005) Subunit assembly of N-Methyl-D-aspartate receptors analyzed by fluorescence resonance energy transfer, Journal of Biological Chemistry, 280(26): 24923-24930