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钱鹏旭

性别:男
职称:百人计划研究员(自然科学C类)
单位:医学院

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发表论文

第一/并列第一作者论文:

1. Qian P, De Kumar B, He XC, Nolte C, Gogol M, Ahn Y, Chen S, Li Z, Xu H, Perry JM, Hu D, Tao F, Zhao M, Han Y, Hall K, Peak A, Dukes D, Paulson A, Venkatraman A, Box A, Perera A, Haug JS, Parmely T, Li H, Krumlauf R, Li L. Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits LeukemogenesisCell Stem Cell. 2018. 

2. Qian P, Li L. Single-cell RNA-seq technology lends a hand into HSC ontogeny. Sci China Life Sci. 2016 Sep;59(9):977-8.

3. Qian P, He XC, Paulson A, Li Z, Tao F, Perry JM, Guo F, Zhao M, Zhi L, Venkatraman A, Haug JS, Parmely T, Li H, Dobrowsky RT, Ding WX, Kono T, Ferguson-Smith AC, Li L. The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism. Cell Stem Cell. 2016 Feb 4;18(2):214-28. (封面文章).

4. Zhang W*, Qian P*, Zhang X, Zhang M, Wang H, Wu M, Kong X, Tan S, Ding K, Perry JK, Wu Z, Cao Y, Lobie PE, Zhu T. Autocrine/paracrine human growth hormone stimulated miRNA 96-182-183 clusters promotes epithelial-mesenchymal transition and invasion in breast cancer. J Biol Chem. 2015 May 29;290(22):13812-29. (*, equal contribution).

5. Liu Y*, Chen C*, Qian P*, Lu X, Sun B, Zhang X, Wang L, Gao X, Li H, Chen Z, Tang J, Zhang W, Dong J, Bai R, Lobie PE, Wu Q, Liu S, Zhang H, Zhao F, Wicha MS, Zhu T, Zhao Y. Gd-metallofullerenol nanomaterial as non-toxic breast cancer stem cell-specific inhibitor. Nat Commun. 2015 Jan 23;6:5988. (*, equal contribution).

6. Banerjee A*Qian P*Wu ZSRen XSteiner MBougen NMLiu SLiu DXZhu TLobie PE. Artemin stimulates radio- and chemo-resistance by promoting TWIST1-BCL-2-dependent cancer stem cell-like behavior in mammary carcinoma cells. J Biol Chem. 2012 Dec 14;287(51):42502-15. (*, equal contribution).

7. Qian PBanerjee AWu ZSZhang XWang HPandey VZhang WJLv XFTan SLobie PEZhu T. Loss of SNAIL regulated miR-128-2 on chromosome 3p22.3 targets multiple stem cell factors to promote transformation of mammary epithelial cells. Cancer Res. 2012 Nov 15;72(22):6036-50. (IF=9.329).

8. Qian P, Zuo Z, Wu Z, Meng X, Li G, Wu Z, Zhang W, Tan S, Pandey V, Yao Y, Wang P, Zhao L, Wang J, Wu Q, Song E, Lobie PE, Yin Z, Zhu T.  Pivotal role of reduced let-7g expression in breast cancer invasion and metastasis. Cancer Res. 2011 Oct 15;71(20):6463-74.  (IF=9.329).

9. Pandey V*, Qian PX*, Kang J, Perry JK, Mitchell MD, Yin Z, Wu ZS, Liu DX, Zhu T, Lobie PE. Artemin stimulates oncogenicity and invasiveness of human endometrial carcinoma cells. Endocrinology. 2010 Mar;151(3):909-20. (*, equal contribution).

其它论文

1. Ding K, Yuan Y, Chong QY, Yang Y, Li R, Li X, Kong X, Qian P, Xiong Z, Pandey V, Ma L, Wu Z, Lobie PE, Zhu T. Autocrine prolactin stimulates endometrial carcinoma growth and metastasis and reduces sensitivity to chemotherapy. Endocrinology. 2017 Feb 15.

2. Ding K, Wu Z, Wang N, Wang X, Wang Y, Qian P, Meng G, Tan S. MiR-26a performs converse roles in proliferation and metastasis of different gastric cancer cells via regulating of PTEN expression. Pathol Res Pract. 2017 Feb 10.

3. Li G, Wu X, Qian W, Cai H, Sun X, Zhang W, Tan S, Wu Z, Qian P, Ding K, Lu X, Zhang X, Yan H, Song H, Guang S, Wu Q, Lobie PE, Shan G, Zhu T. CCAR1 5' UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance. Cell Res. 2016 Jun;26(6):655-73.

4. Kong X, Wu W, Yuan Y, Pandey V, Wu Z, Lu X, Zhang W, Chen Y, Wu M, Zhang M, Li G, Tan S, Qian P, Perry JK, Lobie PE, Zhu T. Human growth hormone and human prolactin function as autocrine/paracrine promoters of progression of hepatocellular carcinoma. Oncotarget. 2016 May 17;7(20):29465-79.

5. Zhang M, Zhang W, Wu Z, Liu S, Sun L, Zhong Y, Zhang X, Kong X, Qian P, Zhang H, Lobie PE, Zhu T. Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma. Oncotarget. 2016 Jan 19;7(3):3267-82.

6. Zhao MPerry JMMarshall HVenkatraman AQian PHe XCAhamed JLi L. Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells. Nat Med. 2014 Nov;20(11):1321-6.

7. Liu DHe XCQian PBarker NTrainor PAClevers HLiu HLi L. Leucine-rich Repeat-containing G-protein Coupled Receptor 5 Marks Short-term Hematopoietic Stem and Progenitor Cells during Mouse Embryonic Development. J Biol Chem. 2014 Aug 22;289(34):23809-16.

8. Ding KBanerjee ATan SZhao JZhuang QLi RQian PLiu SWu ZSLobie PEZhu T. ARTEMIN, a member of the glial cell line-derived neurotrophic factor family of ligands, is HER2 regulated and mediates acquired Trastuzumab resistance by promoting cancer stem cell-like behaviour in mammary carcinoma cells. J Biol Chem. 2014 Jun 6;289(23):16057-16071.

9. Tan SDing KLi RZhang WLi GKong XQian PLobie PEZhu T. Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2. Breast Cancer Res. 2014 Apr 15;16(2):R40.

10. Banerjee AWu ZSQian PXKang JLiu DXZhu TLobie PE. ARTEMIN promotes de novo angiogenesis in ER negative mammary carcinoma through activation of TWIST1-VEGF-A signalling. PLoS One. 2012;7(11):e50098.

11. Banerjee AWu ZSQian PKang JPandey VLiu DXZhu TLobie PE. ARTEMIN synergizes with TWIST1 to promote metastasis and poor survival outcome in patients with ER negative mammary carcinoma. Breast Cancer Res. 2011;13(6):R112. 

12. Wu ZS, Yang K, Wan Y, Qian PX, Perry JK, Chiesa J, Mertani HC, Zhu T, Lobie PE. Tumor expression of human growth hormone and human prolactin predict a worse survival outcome in patients with mammary or endometrial carcinoma.  J Clin Endocrinol Metab. 2011 Oct; 96(10):E1619-29.

13. Pandey V, Jung Y, Kang J, Steiner M, Qian PX, Banerjee A, Mitchell MD, Wu ZS, Zhu T, Liu DX, Lobie PE. Artemin Reduces Sensitivity to Doxorubicin and Paclitaxel in Endometrial Carcinoma Cells through Specific Regulsation of CD24.  Transl Oncol. 2010 Aug 1;3(4):218-29.

14. Kang J, Qian PX, Pandey V, Perry JK, Miller LD, Liu ET, Zhu T, Liu DX, Lobie PE. Artemin is estrogen regulated and mediates antiestrogen resistance in mammary carcinoma. Oncogene. 2010 Jun 3;29(22):3228-40.

15. Kang J, Perry JK, Pandey V, Fielder GC, Mei B, Qian PX, Wu ZS, Zhu T, Liu DX, Lobie PE. Artemin is oncogenic for human mammary carcinoma cells. Oncogene. 2009 May 14;28(19):2034-45.