个人简介

个人简介:许迎科,1982出生于浙江。2008年毕业于浙江大学生物医学工程专业,获博士学位。2008年至2012年,于美国耶鲁大学医学院从事博士后研究工作。2012年年回国任教至今,获浙江大学求是青年学者称号,主要从事生物医学光子学及细胞生物学的应用研究工作。2016.6-至今  担任美国耶鲁大学访问副教授,开展超高分辨活细胞成像方面的课题合作研究。


学术兼职:纽约科学院(NYAS),美国糖尿病学会(ADA),美国细胞生物学学会(ASCB),中国细胞生物学学会(CSCB),中国生物物理学会(BSC),中国生物医学工程学会,F1000 Assoicate Faculty Member,Journal of Cellular and Molecular Medicine (IF=4.9; Associate Editor),JSM Internal Medicine (Editorial Board Member)



代表性论文:

  • Fan J, Zhou X, Wang Y, Kuang C, Sun Y, Liu X, Toomre D, Xu Y*. (2017) Differential requirement for NSF in endosomal trafficking of transferrin receptor from anterograde trafficking of VSVG. FEBS Letters 591, 273-281. (Editor’s Highlights)
  • Li H, Ou L, Fan J, Xiao M, Kuang C, Liu X, Sun Y, Xu Y*. (2017) Rab8A regulates insulin-stimulated GLUT4 trafficking in C2C12 myoblasts. FEBS Letters 591, 491-499.  (Editor’s Choice)
  • Xu Y*, Nan D, Fan J, Bogan JS, Toomre D*. (2016) Optogenetic activation reveals distinct roles of PI(3,4,5)P3 and Akt in adipocyte insulin action. Journal of Cell Science. 129, 2085-2095. 
  • Chenouard N, Smal I, Chaumont F, et al. Liang L, Duncan J, Shen H, Xu Y, et al. Olivo-Marin J, Meijering E. (2014) Objective comparison of particle tracking methods. Nature Methods 11, 281-290. Cover Story
  • Zhang Y, Tang W, Zhang H, Niu X, Xu Y, Zhang J, Gao K, Pan W, Boggon TJ, Toomre D, Min W, Wu D. (2013) A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils. Developmental Cell 27, 215-226.
  • Wang Y, Kuang C, Gu Z, Xu Y, Li S, Hao X, Liu X. (2013) Time-gated stimulated emission depletion nanoscopy. Optical Engineering 52, 093107-093107.
  • Bogan JS, Xu Y, Hao M. (2012) Cholesterol accumulation increases insulin granule size and impairs membrane trafficking. Traffic 11, 1466-1480.
  • Xu Y, Melia TJ, Toomre DK. (2011) Using light to see and control membrane traffic. Current Opinion in Chemical Biology 15, 822-830. 
  • Xu Y, Rubin BR, Orme CM, Karpikov A, Yu C, Bogan JS, Toomre DK (2011) Dual-mode of insulin action controls GLUT4 vesicle exocytosis. Journal of Cell Biology 193, 643-653. 
  • Feng L, Xu Y, Yang Y, Zheng X (2011) Multiple dense particle tracking in fluorescence microscopy images based on multidimensional assignment. Journal of Structural Biology 173, 219-228.  
  • Deng N, Xu Y, Sun DY, Hua PF, Zheng XX, Duan HL (2009) Image processing for fusion identification between the GLUT4 storage vesicles and plasma membrane. Journal of Signal Processing Systems 54, 115-125. 
  • Xu Y, Xu K, Li J, Feng L, Zheng X (2007) Bi-directional transport of GLUT4 vesicles near the plasma membrane of primary rat adipocytes. Biochemical and Biophysical Research Communications 359(1), 121-128. 

国际会议:

  • Xu Y, Toomre DK. Optogenetic control of GLUT4 trafficking. The 3rd International & 12th National Symposium on Membrane Biology. (Zhuhai, China, Nov 2012) (Best Poster Award)
  • Liang L, Shen H, Xu Y, De Camilli P, Toomre DK, Duncan JS. A Bayesian method for 3D estimation of subcellular particle features in multi-angle TIRF microscopy. 2012 International Symposium on Biomedical Imaging. (Paper accepted, Barcelona, Spain; May 2012) 
  • Liang L, Xu Y, Shen H, Toomre DK, De Camilli P, Duncan JS. Automatic detection of subcellular particles in fluorescence microscopy via feature clustering and Bayesian analysis. 2012 IEEE Workshop on the Application of Computer Vision. (Paper accepted, Breckenridge CO; January 2012) 
  • Xu Y, Rubin BR, Orme CM, Karpikov A, Yu C, Bogan JS, Toomre DK. Dual-mode of insulin action controls GLUT4 vesicle exocytosis. 2011 ASCB Annual Meeting (Poster accepted, Denver CO, December 2011)
  • Xu Y, Polejaev V, Toomre DK. Novel multi-angle TIRFM system and its application for studying single vesicle exocytosis. Yale MCGD Track Open House (Poster, September 2011)
  • Xu Y.  Seeing exocytosis in action and studying its dysfunction in diabetes. Yale University Cell Biology Department Annual Retreat (Oral Presentation, December 2010)  
  • Xu Y. Dual-mode of insulin action controls GLUT4 vesicle exocytosis. Yale University Cell Biology Department Progress Report Seminars (Oral Presentation, March 2010)   
  • Goss JW, Fernandes C, Xu Y, Toomre DK. Functional role for the mammalian exocyst complex subunits during constitutive exocytosis. Yale University Cell Biology Department Annual Retreat(Poster, December 2009)  

工作研究领域

生物物理;定量与系统生理学;活细胞显微成像技术;囊泡转运机制;光学遗传学;膜生物学

联系方式

电话:0571-87951091 (Office); 0571-87951091 (Fax)
电子信箱:yingkexu@zju.edu.cn