Education:

2005 – 2012 Shanghai Institutes for Biochemistry and Cell Biology (Ph.D.)

2005 ~ 2006: Courses learning and lab rotation.

2007 ~ 2012: In Dr. Gang Pei’s lab, research projects:

1. GPCR and Alzheimer’s Disease 2. β-arrestins and Obesity

2001 – 2005 Life Science College, Shaanxi Normal University (B.S.)

Research experience:

2019 – now, Assistant Professor in College of Animal Sciences, Zhejiang University, China

• Genetics and epigenetics regulation of tissue development and function

• Animal disease models about energy metabolism

2018 – 2019, Assistant instructor in Dr. Eric Olson’s lab in UT Southwestern Medical Center

• Transcriptional regulation of muscle remodeling in response to exercise 2018

▫ ChIP-Seq and RNA-Seq show the important role of epigenetic regulation on muscle remodeling in response to exercise.

• Characterize role of muscle specific gene Tmem233 and Txlnb in muscle development and function 2018

▫ Identified muscle specific gene Tmem233 and Txlnb; Generated knockout mice and transgenic mice to decipher the role of Tmem233 and Txlnb in muscle development and function.

2013 – 2018, Postdoctoral in Dr. Kai Ge’s lab in NIDDK/ National Institutes of Health.

• Transcriptional programming of adipose tissue development and function by histone H3K36 methyltransferase Nsd2 and histone H3K36 methylation 2018

• Important role of MLL4 in regulating enhancer activation during cell differentiation 2017

• Innate and adaptive lymphocytes shape the gut microbiota and lipid metabolism. 2017

• Gcn5 negatively regulate IFNβ production through HAT‐independent inhibition of TBK1 2015

• UTX demethylase activity is required for satellite cell–mediated muscle regeneration 2015

• CRISPR-mediated enhancer deletion to probe the role of enhancers during adipogenesis 2014