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2021-06-30
:6440
HuangLiquan Ph.D.
Professor | Doctoral supervisor
Lab Head
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  • +8657188981755
  • Room 337 College of Life Sciences Building
    • Molecular biology of taste and olfactory perception

Education:     

                     Sep. 1991--July 1996       Department of Biology, Yale University

                                                                      M.Ph. in Biology, June 1993

                                                                                            Ph.D. in Molecular Biology, July 1996

                     Jan. 1991--Aug. 1991    Department of Cell Biology and Anatomy

                                                                                             New York Medical  College

                     Sep. 1984--Oct. 1987     Institute of Genetics Academia Sinica,

                   M.Sc. in Molecular Genetics, Oct. 1987

                        Sep. 1980--July 1984       Biology Department

                            Zhejiang (formerly Hangzhou) University, China

                                                                                            B.Sc. in Biology, July 1984

Training:  

                    Aug 1996-Oct 2000        Postdoctoral Training

                                                                 Department of Physiology and Biophysics

                                                                 Mount Sinai School of Medicine

                                                                New York University

                                                                (Advisor: Dr. Robert F. Margolskee)

                        Professional Positions:

        2013-present  Professor, PhD Advisor, Zhejiang University, Hangzhou, China

        2013-present  Adjunct Member, University of Pennsylvania-affiliated Monell

                                          Chemical Senses Center, Philadelphia, USA

        2011-2013       Director, Monell Histology and Cellular Localization Core

        2010-2013       Chair, Monell Institutional Biosafety Committee

  2010-2016       Adjunct Professor, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

  2008-2013       Associate Member, UPenn-affiliated Monell Chemical Senses Center, Philadelphia, USA

  2002-2013       Member, Penn Genome Frontiers Institute, UPenn, Philadelphia, USA

  2002-2008       Assistant Member, UPenn-affiliated Monell Chemical Senses Center, Philadelphia, USA

  2000-2002       Instructor, Department of Physiology and Biophysics, Mount  Sinai School of Medicine, New York University, NY

  1987-1990       Assistant Researcher, Institute of Genetics, Academia Sinica,  Beijing, China

                    Research Programs:

Dr. Huang has been working on the molecular biology of taste and smell for many years. In 1996, he established and optimized single taste bud cell transcriptome analysis method and made many important findings, which were published in two Nature Neuroscience papers and one Nature Genetics paper. Thus, he is one of the first scientists who could successfully utilize this powerful single cell approach. His ongoing projects are mostly focused on the regeneration of mamalian taste bud cells and olfactory sensory neurons, and the function of taste and olfactory receptors and their signaling proteins in extra-oral/-nasal tissues, including:

    • The effect of taste signal transduction interruption on the proliferation and differentiation of gustatory stem cells

    • Regulation of olfactory stem cells’ proliferation and differentiation

    • Interactions between taste/olfactory receptors and their ligands and its correlation with ligands’ toxicity

    • Interactions between taste/olfactory receptors and pathogenic microbes

    • Expression and function of taste/olfactory receptors and their signaling proteins in the extra-oral/nasal organs and organoids

Postdoctoral positions are available. Qualified candidates are welcome to contact the PI: huangliquan@zju.edu.cn

Graduate students for a PhD or MS degree are welcome to apply

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