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来建波 博士
硕士生导师 | /
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2024-04-09 | 3374
  • 13732254858
  • 杭州市上城区城站路58号精神卫生科医生办公室
    • · 情感障碍的神经免疫和脑-肠轴机制
    • · 精神康复

个人简介

男,医学博士,浙江大学精神病与精神卫生学硕士生导师。

浙江大学医学院附属第一医院精神卫生科 主治医师,特聘研究员。

Elsevier2022中国高被引学者,入选第六版全球前2%顶尖科学家榜单(World's Top 2% Scientists 2022)“2022年度科学影响力排行榜”(single-year impact), H-index 14,累计被引次数超5000次(web of science)。

获“中国精神医学杰出青年医生”荣誉(2023年)。

主持国家自然科学青年基金、省自然科学基金、省卫健委项目各1项,浙江省重大研发计划项目子课题1项,参与国家自然科学基金4项、省公益项目1项、省卫生厅平台重点项目1项。已发表SCI论文/评述86篇,其中通讯作者17篇,第一作者16篇,共同第一作者13篇。《中华精神科杂志》、Neuropsychiatric disease and treatment、Asia-Pacific Psychiatry、Sleep Medicine、Psychology Research and Behavior Management、JAMA Network Open、Culture, Medicine, and Psychiatry、Psychiatria Danubina、Frontiers in Psychiatry、Frontiers in Neurology、Frontiers in Pediatrics、CNS Neuroscience & Therapeutics、Brain and Behavior、Brain, Behavior, & Immunity - Health、Heliyon、iMeta、Brain-X、Psychoradiology、Annals of Medicine、Expert Opinion On Pharmacotherapy等期刊审稿人。BMJ Mental Health Associate Editor, BMC Medicine、BMC Psychiatry期刊编委、iMeta和Brain-X期刊青年编委、《解放军医学杂志》 第二/三届青年编委。

教学与课程

参与讲授本科生《精神病学》课程、研究生《高级心理学》和《精神科与精神卫生学进展》等课程。

教育经历

2009/9 - 2016/6,浙江大学,临床医学七年制,硕士,导师:胡少华

2019/9 - 2022/3,浙江大学,精神病与精神卫生学,在职博士研究生,导师:胡少华

研究与成果

1、国家自然科学基金青年项目,82201676,肠道微生物抑制PI3K/Akt/GSK-3β通路上调海马TRANK1表达介导双相抑郁的神经病理机制,2023.1.1-2025.12.31,30万元,主持

2、浙江省重点研发计划 子课题,2021C03107,神经精神疾病诊治新技术研究-情感障碍认知损害诊治新技术研究, 2021.1.1-2023.12.31,50万元,子课题负责人

3、浙江省自然科学基金项目,LQ20H090013,Toll样受体4介导的神经炎症在双相抑郁脑-肠轴调节中的作用研究,2020/01-2022/12,9万元,主持

4、浙江省卫健委面上项目,2020KY548,肠道菌群参与二甲双胍改善抗精神病药物相关代谢综合征的机制研究,2020/01-2022/12,主持

5、国家自然科学基金面上项目,81971271,肠道拟杆菌及TIM-3介导双相障碍炎症反应的机理研究,2020/01-2023/12,55万元,在研,参加

6、国家自然科学基金面上项目,81771474,ZNF536基因调控视黄酸介导的性取向多态性的机制研究,2018/01-2021/12,54万元,在研,参加

7、国家自然科学基金面上项目,81676357,FMR1NB基因多态性和男性同性恋杏仁核结构和功能的相关性研究,2017/01-2020/12,57万元,在研,参加

8、国家自然科学基金青年项目,81601182,伴童年创伤抑郁症炎症系统活性和情绪相关脑区影像特征及其关联性研究,2017/01-2019/12,17万元,已结题,参加

9、浙江省公益技术研究社会发展项目,2015C33133,催产素对男性性取向影响的研究,2015/07-2017/12,15万,已结题,参加

10、浙江省医药卫生科技计划项目,2014KY1001004, 神经性厌食症患者情绪调节环路的脑影像学研究,2014/06-2017/12,5万元,已结题,参加

工作经历

2016/8 - 2019/12,浙江大学,医学院附属第一医院,精神卫生科,住院医师

2020/1 - 至今,浙江大学,医学院附属第一医院,精神卫生科,主治医师

2022/12 - 至今, 浙江大学,医学院附属第一医院,精神卫生科,特聘研究员

学术任职

中华医学会精神病学分会生物精神病学组 委员

中华医学会精神病学分会精神康复协作组 委员

浙江省发明协会精神医学专业委员会 委员

浙江省康复医学会精神康复专业委员会 委员

浙江省康复医学会临床心理治疗专业委员会 委员

浙江省康复医学会心身康复专业委员会 委员

浙江省数理医学会脑肠微生物轴基础与临床专业委员会 副秘书长、青委副主委

浙江省生物医学学会生物精神病专业委员会(筹)秘书长


学术会议

1、2021年国际卒中年会,特邀报告,“Mental health stressors and aftermath”. 线上,2021.3.17~2021.3.19.

2、2021年中国情感障碍大会,分会场报告,“Circulating T-cell Subsets Discrepancy Between Bipolar Disorder and Major Depressive Disorder: A Naturalistic, Retrospective Study of 1015 Cases”,贵州贵阳,2021.10.14~2021.10.16.

3、2021年中华医学会第十九次全国精神医学学术会议暨第十五次全国儿童青少年精神医学大会,分会场报告,“Deciphering gut microbes and sensory-emotional functional disruption in unmedicated adolescent bipolar depression”,重庆,2021.12.21~2021.12.24.

4、2022年浙江省神经科学学会第十届学术年会,青年博士论坛,“基于多组学的双相抑郁脑肠轴病理机制研究”,杭州,2022.7.8~2022.7.9.

5、中国医师协会精神科医师分会第十九届年会(CPA2023),壁报交流,“中国精神康复政策30年(1994-2023)发展史”,武汉,2023.5.25-2023.5.27.

6、首届东方精神医学大会暨2023中国情感障碍大会,口头报告,“双相障碍的全球疾病负担”,上海,2023.8.18~2023.8.20.



获得荣誉

2017年度浙大一院优秀住院医师

2019年度院级先进工作者

2020年浙江省科技进步二等奖(排名5/9)

2021年中国情感障碍大会优秀论文二等奖,优秀壁报

《2021年中国科技论文统计报告》,“Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019”获评2020年度“中国百篇最具影响国际学术论文”

2022年热心肠奖学金(临床医学)三等奖

2022年浙江省神经科学学会第十届学术年会,青年博士论坛,临床组一等奖

2023年 第十七届 浙江大学林百欣高科技奖 三等奖

2023年 获“中国精神医学杰出青年医生”荣誉

发表文章

通讯作者文章(17篇)

Li S, Xu C, Hu S*, Lai J*. Efficacy and tolerability of FDA-approved atypical antipsychotics for the treatment of bipolar depression: a systematic review and network meta-analysis. Eur Psychiatry. 2024 Mar 15:1-26. doi: 10.1192/j.eurpsy.2024.25.


Kong L, Chen Y, Shen Y, Zhang D, Wei C, Lai J*, Hu S*. Progress and Implications from Genetic Studies of Bipolar Disorder. Neurosci Bull. 2024 Jan 11. doi: 10.1007/s12264-023-01169-9.


Li S, Lv D, Qian C, Jiang J, Zhang P, Xi C, Wu L, Gao X, Fu Y, Zhang D, Chen Y, Huang H, Zhu Y, Wang X, Lai J*, Hu S*. Circulating T-cell subsets discrepancy between bipolar disorder and major depressive disorder during mood episodes: A naturalistic, retrospective study of 1015 cases. CNS Neurosci Ther. 2024;30(2):e14361.


Kong L, Shen Y, Hu S*, Lai J*. The impact of quetiapine monotherapy or in combination with lithium on the thyroid function in patients with bipolar depression: A retrospective study. CNS Neurosci Ther. 2024;30(2):e14342.


Kong LZ, Lai JB*, Hu SH*. China released the latest national mental health report: A blueprint for the future. Asian J Psychiatr. 2023;85:103624.

 

Shen Y, Kong L, Lai J*, Hu S*. Shifting levels of peripheral inflammatory profiles as an indicator for comorbid multiple autoimmune diseases and bipolar disorder: a case report. BMC Psychiatry. 2023;23(1):375.


Chen N, Li S, Huang S, Lai J*, Lv D*. Clinical characteristics and outcomes of patients with mental illnesses who attempted suicide by drug overdose: A retrospective analysis of 109 cases. Brain Behav. 2023:e3058.


Li S, Huang S, Hu S*, Lai J*. Psychological consequences among veterans during the COVID-19 pandemic: A scoping review. Psychiatry Res. 2023;324:115229.


Zhang R, Lai J*, Wang H. An Integrative Model of In-Hospital and Out-of-Hospital Nursing Care for Non-Suicidal Self-Injury: A Narrative Review. Brain Sci. 2023;13(3):466. 


Kong L, Zhang D, Huang S, Lai J*, Lu L*, Zhang J*, Hu S*. Extracellular Vesicles in Mental Disorders: A State-of-art Review. Int J Biol Sci. 2023 Feb 5;19(4):1094-1109.


Kong LZ, Shen YT, Zhang DH, Lai JB*, Hu SH*. Free long-acting injectables for patients with psychosis: A step forward. Asian J Psychiatr. 2023 Jan 20;83:103476. (IF2021=13.89)


Jiang J, Fu Y, Tang A, Gao X, Zhang D, Shen Y, Mou T, Hu S*, Gao J*, Lai J*. Sex difference in prebiotics on gut and blood-brain barrier dysfunction underlying stress-induced anxiety and depression. CNS Neurosci Ther. 2023 Jan 17. doi: 10.1111/cns.14091. (IF2021=7.035)


Li S, Zhang R, Hu S*, Lai J*. Plasma Orexin-A Levels in Patients With Schizophrenia: A Systematic Review and Meta-Analysis. Front Psychiatry. 2022;13:879414. (IF2021=5.435)

 

Diao X, Wang D, Lu S, Hu S*, Lai J*. A Case of Hyperpyrexia Associated With Risperidone Microspheres for Injection (II). J Clin Psychopharmacol. 2022. 42(3):325-327. (IF2021=3.118)

 

Kong LZ, Zhang RL, Hu SH*, Lai JB*. Military traumatic brain injury: a challenge straddling neurology and psychiatry. Mil Med Res. 2022;9(1):2. (IF2021=34.915)

 

Zhang R, Li S, Lai J*, Wang H*. Mania in a Patient With Pituitrin-Associated Hyponatremia. J Clin Psychopharmacol. 2022;42(2):219-221. (IF2021=3.118)

 

Wang X, Huang H, Zhu Y, Li S, Zhang P, Jiang J, Xi C, Wu L, Gao X, Fu Y, Zhang D, Chen Y, Hu S*, Lai J*. Metformin acts on the gut-brain axis to ameliorate antipsychotic-induced metabolic dysfunction. Biosci Trends. 2021; 15(5):321-329. (IF2021=9.083)

 

第一作者文章(16篇)

Lai J#, Li S#, Wei C#, Chen J, Fang Y*, Song P*, Hu S*. Mapping the global, regional and national burden of bipolar disorder from 1990 to 2019: trend analysis on the Global Burden of Disease Study 2019. Br J Psychiatry. 2024 Feb;224(2):36-46.


Lai JB, Kong LZ, Chen J, Hu SH. From strict quarantine to an optimized policy: Are we psychologically prepared? Asian J Psychiatr. 2022;81:103435. (IF2021=13.89)


Lai J, Zhang P, Jiang J, Mou T, Li Y, Xi C, Wu L, Gao X, Zhang D, Chen Y, Huang H, Li H, Cai X, Li M, Zheng P, Hu S. New Evidence of Gut Microbiota Involvement in the Neuropathogenesis of Bipolar Depression by TRANK1 Modulation: Joint Clinical and Animal Data. Front Immunol. 2021;12:789647.  IF2021=8.786

 

Lai J, Li A, Jiang J, Yuan X, Zhang P, Xi C, Wu L, Wang Z, Chen J, Lu J, Lu S, Mou T, Zhou H, Wang D, Huang M, Dong F, Li MD, Xu Y, Song X, Hu S. Metagenomic analysis reveals gut bacterial signatures for diagnosis and treatment outcome prediction in bipolar depression. Psychiatry Res. 2022;307:114326.IF2021=11.225

 

Lai J, Jiang J, Zhang P, Xi C, Wu L, Gao X, Fu Y, Zhang D, Chen Y, Huang H, Zhu Y, Hu S. Impaired blood-brain barrier in the microbiota-gut-brain axis: Potential role of bipolar susceptibility gene TRANK1. J Cell Mol Med. 2021;25(14):6463-6469. IF2021=5.295

 

Lai J, Jiang J, Zhang P, Xi C, Wu L, Gao X, Zhang D, Du Y, Li Q, Diao X, Lu S, Wang Z, Song X*, Hu S*. Gut microbial clues to bipolar disorder: state-of-the-art review of current findings and future directions. Clin Transl Med. 2020;10:e146. IF2020=11.492

 

Lai J, Ma S, Wang Y, Cai Z, Hu J, Wei N, Wu J, Du H, Chen T, Li R, Tan H, Kang L, Yao L, Huang M, Wang H, Wang G, Liu Z, Hu S. Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease 2019. JAMA Netw Open. 2020;3(3):e203976. IF2020=8.483 ESI高被引论文、热点论文,引用超4000

 

Lai J, Xu T, Zhang H, et al. Fractional amplitude of low frequency fluctuation in drug-naïve first-episode patients with anorexia nervosa: A resting-state fMRI study. Medicine (Baltimore). 2020;99(9):e19300. IF2020=1.889

 

Lai JB, Hu SH. China sets up the Specialized Committee of Mental Health Rehabilitation. Lancet Psychiatry. 2020.7(1):20.IF2020=27.083

 

Lai J, Xu Z, Xu Y, Hu S. Reframing delusional infestation: perspectives on unresolved puzzles. Psychol Res Behav Manag. 2018;11:425-432. IF2018=1.84

 

Lai J, Zhou W, Lu Q, Huang T, Xu Y, Hu S. Laxative use and clinical correlates in hospitalized patients with obsessive-compulsive disorder: a retrospective descriptive study. Neuropsychiatr Dis Treat. 2018;14:933-936. IF2018=2.228

 

Lai JB, Han MM, Xu Y, Hu SH. Effective treatment of narcolepsy-like symptoms with high-frequency repetitive transcranial magnetic stimulation: A case report. Medicine (Baltimore). 2017;96(46):e8645. IF2017=2.028

 

Lai J, Lu Q, Huang T, Hu S, Xu Y. Convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder. Neuropsychiatr Dis Treat. 2017;13:1905-1908. IF2017=2.195

 

Lai J, Lu Q, Zhang P, Xu T, Xu Y, Hu S. Aripiprazole augmentation in managing comorbid obsessive-compulsive disorder and bipolar disorder: a case with suicidal attempts. Neuropsychiatr Dis Treat. 2016;13:87-90. IF2016=2.198

 

Lai J, Lu Q, Xu Y, Hu S. Severe water intoxication and secondary depressive syndrome in relation to delusional infestation. Neuropsychiatr Dis Treat. 2016;12:517-21. IF2016=2.198

 

Lai J, Xu D, Peterson BS, Xu Y, Wei N, Zhang M, Hu S. Reversible Fluoxetine-Induced Hyperthyroidism: A Case Report. Clin Neuropharmacol. 2016;39(1):60-1. IF2016=1.451

 

共同第一文章(13篇)

Zhang P#, Zhang D#, Lai J#, Fu Y, Wu L, Huang H, Pan Y, Jiang J, Xi C, Che Z, Song X*, Hu S*. Characteristics of the gut microbiota in bipolar depressive disorder patients with distinct weight. CNS Neurosci Ther. 2023 Jan 5. doi: 10.1111/cns.14078.  (IF2021=7.035)


Li Z#, Lai J#, Zhang P#, Ding J#, Jiang J, Liu C, Huang H, Zhen H, Xi C, Sun Y, Wu L, Wang L, Gao X, Li Y, Fu Y, Jie Z, Li S, Zhang D, Chen Y, Zhu Y, Lu S, Lu J, Wang D, Zhou H, Yuan X, Li X, Pang L, Huang M, Yang H, Zhang W, Brix S, Kristiansen K, Song X, Nie C, Hu S. Multi-omics analyses of serum metabolome, gut microbiome and brain function reveal dysregulated microbiota-gut-brain axis in bipolar depression. Mol Psychiatry. 2022. doi: 10.1038/s41380-022-01569-9. (IF2021=13.437)

 

Kong LZ#, Lai JB#, Hu SH*. China initiates depression screening in children and adolescents. Lancet Psychiatry. 2022;9(2):107-108. IF2021=77.056

 

Zhang R#, Lai J#, Wang Y#, Huang J, Hu S*, Wang H*. Mental health outcome and resilience among aiding Wuhan nurses: One year after the COVID-19 outbreak in China. J Affect Disord. 2022;297:348-352. IF2021=6.533

 

Wang Y#, Lai J#, Hu C, Meng H, Lyu D, Hu S*. Non-suicidal self-harm is linked to suicidal thoughts in Chinese adolescents with mood disorders: a cross-sectional report. J Zhejiang Univ Sci B. 2021;22(3):233-240. IF2021=3.066

 

Xi C#, Lai J#, Du Y, Ng CH, Jiang J, Wu L, Zhang P, Xu Y, Hu S*. Abnormal functional connectivity within the reward network: a potential neuroimaging endophenotype of bipolar disorder. J Affect Disord. 2021;280(Pt B):49-56. IF2021=6.533

 

Zhang R, Lai J, Huang J. Acute onset of orofacial dystonia from promethazine treatment: A case report. Medicine (Baltimore). 2019;97(46):e17675. IF2018=1.87

 

Li C, Lai J, Huang T, Han Y, Du Y, Xu Y, Hu S. Thyroid functions in patients with bipolar disorder and the impact of quetiapine monotherapy: a retrospective, naturalistic study. Neuropsychiatr Dis Treat. 2019;15:2285-2290. IF2018=2.228

 

Huang TT, Lai JB, Du YL, Xu Y, Ruan LM, Hu SH. Current Understanding of Gut Microbiota in Mood Disorders: An Update of Human Studies. Front Genet. 2019;10:98. (IF2018=3.517)

 

Wang D, Lai J, Lu S, Huang M, Hu S, Xu Y. Rapid-onset hyponatremia and delirium following duloxetine treatment for postherpetic neuralgia: Case report and literature review. Medicine (Baltimore). 2018;97(46):e13178. IF2018=1.87

 

Zhou W, Lai J, Huang T, Xu Y, Hu S. Cryptococcal meningitis mimicking cerebral infarction: a case report. Clin Interv Aging. 2018;13:1999-2002. IF2016=2.585

 

Hu J, Lai J, Hu S, Xu Y. Scopolamine alleviates involuntary lingual movements: tardive dyskinesia or dystonia? Neuropsychiatr Dis Treat. 2017;13:2327-2330. IF2017=2.195

 

Hu J, Lai J, Zheng H, Hu S, Xu Y. Fan the flame: trazodone-induced mania in a unipolar depressed patient with stable sertraline treatment. Neuropsychiatr Dis Treat. 2017;13:2251-2254. IF2017=2.195

 

其他文章(40篇)

Geng Y, Zhang P, Pan Y, Wang H, Chen Y, Lai J, Hu S. Clinical Characteristics of Asymptomatic Thromboembolism in Psychiatric Inpatients: A Retrospective Study. Neuropsychiatr Dis Treat. 2024;20:515-522. 


Lyu H, Huang H, He J, Zhu S, Hong W, Lai J, Gao T, Shao J, Zhu J, Li Y, Hu S. Task-state skin potential abnormalities can distinguish major depressive disorder and bipolar depression from healthy controls. Transl Psychiatry. 2024;14(1):110. 


Zhu Y, Wu L, Ye S, Fu Y, Huang H, Lai J, Shi C, Hu S. The Chinese Version of Oxford Depression Questionnaire: A Validation Study in Patients with Mood Disorders. Neuropsychiatr Dis Treat. 2023 Mar 7;19:547-556. 


Yang S, Zhang YF, Lu SJ, Ye ZQ, Lai JB, Li L, Yang X, Wang DD, Zhang PF, Wu LL, Huang HM, Gao XL, Wu M, Pan YM, Chen YQ, Zhang DH, Geng YM, Zhao QW, Hu SH. Relationship between serum concentration and clinical response of quetiapine in adolescents and adults with bipolar disorders in acute stage: a prospective observational study. J Affect Disord. 2022 Dec 29;324:199-205. IF2021=6.533


Diao X, Luo D, Wang D, Lai J, Li Q, Zhang P, Huang H, Wu L, Lu S, Hu S. Lurasidone versus Quetiapine for Cognitive Impairments in Young Patients with Bipolar Depression: A Randomized, Controlled Study. Pharmaceuticals (Basel). 2022 Nov 14;15(11):1403. (IF2021=5.215


Xi C, Li A, Lai J, Huang X, Zhang P, Yan S, Jiao M, Huang H, Hu S. Brain-gut microbiota multimodal predictive model in patients with bipolar depression. J Affect Disord. 2022 Nov 15:S0165-0327(22)01273-3. doi: 10.1016/j.jad.2022.11.026. IF2021=6.533


Li Y, Zhang H, Zheng P, Yang J, Wu J, Huang Y, Hu X, Tan X, Duan J, Chai T, Zhou J, Sun Z, Liu M, Lai J, Huang T, Du Y, Zhang P, Sun W, Ding Y, Luo C, Zhao J, Perry SW, Wong ML, Licinio J, Hu S, Xie P, Wang G. Perturbed gut microbiota is gender-segregated in unipolar and bipolar depression. J Affect Disord. 2022;317:166-175.  IF2021=6.533)


Huang H, Zhang P, Wu L, Lai J, Hu S. Gastrointestinal Hemorrhage After Antidepressant Drug Use: A Case Report. J Clin Psychopharmacol. 2022;42(3):333-335. (IF2021=3.118)

 

Zhang P, Tang A, Geng Y, Lai J, Gao X, Pan Y, Huang H, Jiang J, Zhang D, Xi C, Wu L, Hu S. Gut microbial trajectory in patients with bipolar depression: A longitudinal study. Asian J Psychiatr. 2022;73:103098. (IF2021=13.89)

 

Zhang P, Kong L, Huang H, Pan Y, Zhang D, Jiang J, Shen Y, Xi C, Lai J, Ng CH, Hu S. Gut Microbiota - A Potential Contributor in the Pathogenesis of Bipolar Disorder. Front Neurosci. 2022;16:830748. (IF2021=5.152)

 

Hu SH, Li HM, Yu H, Liu Y, Liu CX, Zuo XB, Lu J, Jiang JJ, Xi CX, Huang BC, Xu HJ, Hu JB, Lai JB, Huang ML, Liu JN, Xu DG, Guo XC, Wu W, Wu X, Jiang L, Li M, Zhang GP, Huang JW, Wei N, Lv W, Duan JF, Qi HL, Hu CC, Chen JK, Zhou WH, Xu WJ, Liu CF, Liang HY, Du J, Zheng SF, Lu QL, Zheng L, Hu XW, Chen FX, Chen P, Zhu B, Xu LJ, Ni ZM, Fang YZ, Yang ZK, Shan XR, Zheng ED, Zhang F, Zhou QQ, Rao Y, Swaab D, Yue WH, Xu Y. Discovery of new genetic loci for male sexual orientation in Han population. Cell Discov. 2021;7(1):103. IF2021=38.079

 

Zhang P, Huang H, Gao X, Jiang J, Xi C, Wu L, Fu Y, Lai J, Hu S. Involvement of Kynurenine Metabolism in Bipolar Disorder: An Updated Review. Front Psychiatry. 2021;12:677039. IF2021=5.435

 

Wang T, Zhou W, Jiang R, Lai J, Jiang P, Chen X, Li B. Predictive factors associated with disease recurrence in patients with severe intrahepatic cholestasis of pregnancy: a retrospective study of 118 cases. J Matern Fetal Neonatal Med. 2021:1-8. IF2021=2.323

 

Hu CC, Huang JW, Wei N, Hu SH, Hu JB, Li SG, Lai JB, Huang ML, Wang DD, Chen JK, Zhou XY, Wang Z, Xu Y. Interpersonal psychotherapy-based psychological intervention for patient suffering from COVID-19: A case report. World J Clin Cases. 2020;8(23):6064-6070.  IF2020=1.337

 

Yang J, Zheng P, Li Y, Wu J, Tan X, Zhou J, Sun Z, Chen X, Zhang G, Zhang H, Huang Y, Chai T, Duan J, Liang W, Yin B, Lai J, Huang T, Du Y, Zhang P, Jiang J, Xi C, Wu L, Lu J, Mou T, Xu Y, Perry SW, Wong ML, Licinio J, Hu S, Wang G, Xie P. Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders. Sci Adv. 2020;6(49):eaba8555. IF2020=14.136

 

Zhang W, Zhu N, Lai J, Liu J, Ng CH, Chen J, Qian C, Du Y, Hu C, Chen J, Hu J, Wang Z, Zhou H, Xu Y, Fang Y, Shi C, Hu S. Reliability and Validity of THINC-it in Evaluating Cognitive Function of Patients with Bipolar Depression. Neuropsychiatr Dis Treat. 2020;16:2419-2428. IF2020=2.57

 

Du YL, Hu JB, Huang TT, Lai JB, Ng CH, Zhang WH, Li C, Xu ZY, Zhou HT, Ruan LM, Xu Y, Hu SH. Psychometric properties of the Clinically Useful Depression Outcome Scale supplemented with DSM-5 Mixed subtype questionnaire in Chinese patients with mood disorders. J Affect Disord. 2020;279:53-58. IF2020=4.839

 

Wang Z, Hu JB, Ji GJ, Xu DR, Wang DD, Xi CX, Hu CC, Lu J, Du YL, Lu QQ, Huang TT, Lai JB, Chen JK, Zhou WH, Wei N, Xu Y, Wang K, Hu SH*. Executive function and its relation to anatomical connectome in homosexual and heterosexual men. Quant Imaging Med Surg. 2020 Oct;10(10):1973-1983. IF2020=3.837

 

Wu C, Lai J, Ma S, Huang M, Hu S, Xu Y. Paliperidone-Related Sudden Elevation of Plasma D-Dimer Levels: A Case Report. J Clin Psychopharmacol. 2020;40(5):506-507. IF2020=3.153

 

Wu C, Chen X, Lai J, Xu Y, Hu S. The efficacy and safety of sulforaphane as an adjuvant in the treatment of bipolar depressive disorder: Study protocol for a randomized, double-blinded, placebo-controlled, parallel-group clinical trial. Medicine (Baltimore). 2020;99(26):e20981. IF2020=1.889

 

Du Y, Jiang J, Ng CH, Wu L, Zhang P, Xi C, Lai J, Xu Y, Hu S, Wang Z. Vortioxetine improves rapid eye movement sleep behavior disorder: A case report. Medicine (Baltimore). 2020;99(26):e21003. IF2020=1.889

 

Wang D, Han L, Xi C, Xu Y, Lai J, Lu S, Huang M, Hu J, Wei N, Xu W, Zhou W, Lu Q, He H, Hu S. Interactive effects of gender and sexual orientation on cortical thickness, surface area and gray matter volume: a structural brain MRI study. Quant Imaging Med Surg. 2020;10(4):835-846. IF2020=3.837

 

Zheng P, Yang J, Li Y, Wu J, Liang W, Yin B, Tan X, Huang Y, Chai T, Zhang H, Duan J, Zhou J, Sun Z, Chen X, Marwari S, Lai J, Huang T, Du Y, Zhang P, Perry SW, Wong ML, Licinio J, Hu S, Xie P, Wang G. Gut Microbial Signatures Can Discriminate Unipolar from Bipolar Depression. Adv Sci (Weinh). 2020;7(7):1902862. IF2019=15.80

 

Lu S, Ren S, Xu Y, Lai J, Hu J, Lu J, Huang M, Ma X, Chen J, Hu S. China legislates against violence to medical workers. Lancet Psychiatry. 2020;7(3):e9. IF2020=27.083

 

Kang L, Li Y, Hu S, Chen M, Yang C, Yang BX, Wang Y, Hu J, Lai J, Ma X,  Chen J, Guan L, Wang G, Ma H, Liu Z. The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus. Lancet Psychiatry. 2020;7(3):e14. IF2020=27.083

 

Zhang H, Zhang H, Ouyang K, Yan C, Lai J, Hu S. Current status and progress of electroencephalogram study in patients with bipolar disorder. Minerva Med. 2020;111(6):613-614. (IF2010=4.806)

 

Xu Z, Lai J, Zhang H, Ng CH, Zhang P, Xu D, Hu S. Regional homogeneity and functional connectivity analysis of resting-state magnetic resonance in patients with bipolar II disorder. Medicine (Baltimore) 2019;98(47): e17962. IF2018=1.87

 

Lu Q, Lai J, Lu H, Ng C, Huang T, Zhang H, Ding K, Wang Z, Jiang J, Hu J, Lu J, Lu S, Mou T, Wang D, Du Y, Xi C, Lyu H, Chen J, Xu Y, Liu Z, Hu S. Gut microbiota in bipolar depression and its relationship to brain function: an advanced exploration. Frontiers in Psychiatry. 2019;10:784. (IF2018=3.161)

 

Hu SH, Li A, Huang TT, Lai JB, Li JJ, M. Elizabeth Sublette, Lu QQ, Du YL, Hu ZY, Chee H. Ng, Zhang H, Lu J, Mou TT, Lu SJ, Wang DD, Duan JF, Hu JB, Huang ML, Wei N, Zhou WH, Ruan LM, Li MD, Xu Y. Gut Microbiota changes in patients with bipolar depression. Advanced Science. 2019;6(14):1900752. IF2018=15.804

 

Lu Q, Lai J, Du Y, Huang T, Prukpitikul P, Xu Y, Hu S. Sexual dimorphism of oxytocin and vasopressin in social cognition and behavior. Psychol Res Behav Manag. 2019;12:337-349. IF2018=1.84

 

Duan J, Lai J, Wang D, Zhou W, Huang M, Hu S, Xu Y, Lu J. Topiramate precipitating a manic episode in a bipolar patient comorbid with binge eating disorder: A case report. Medicine (Baltimore). 2019;98(17):e15287. IF2018=1.87

 

Hu SH, Han YQ, Mou TT, Huang ML, Lai JB, Ng CH, Lu J, Lu QQ, Lin QY, Zhang YZ, Hu JB, Wei N, Xu WJ, Zhou WH, Chen JK, Hu CC, Zhou XY, Lu SJ, Xu Y. Association of Genetic Polymorphisms with Age at Onset in Han Chinese Patients with Bipolar Disorder. Neurosci Bull.2019;35: 591-594. IF2018=4.246

 

Hu SH, Feng H, Xu TT, Zhang HR, Zhao ZY, Lai JB, Xu DR, Xu Y. Altered microstructure of brain white matter in females with anorexia nervosa: a diffusion tensor imaging study. Neuropsychiatr Dis Treat. 2017;13:2829-2836. IF2017=2.195

 

Wu W, Zheng YL, Tian LP, Lai JB, Hu CC, Zhang P, Chen JK, Hu JB, Huang ML, Wei N, Xu WJ, Zhou WH, Lu SJ, Lu J, Qi HL, Wang DD, Zhou XY, Duan JF, Xu Y, Hu SH. Circulating T lymphocyte subsets, cytokines, and immune checkpoint inhibitors in patients with bipolar II or major depression: a preliminary study. Sci Rep. 2017;7:40530. IF2017=4.122

 

Hu SH, Lai JB, Xu DR, Qi HL, Peterson BS, Bao AM, Hu CC, Huang ML, Chen JK, Wei N, Hu JB, Li SL, Zhou WH, Xu WJ, Xu Y. Efficacy of repetitive transcranial magnetic stimulation with quetiapine in treating bipolar II depression: a randomized, double-blinded, control study. Sci Rep. 2016;6:30537. IF2017=4.259

 

Wang LF, Huang JW, Shan SY, Ding JH, Lai JB, Xu Y, Hu SH. Possible sertraline-induced extrapyramidal adverse effects in an adolescent. Neuropsychiatr Dis Treat. 2016;12:1127-9. IF2016=2.198

 

Wei N, Lai J, Xu D, Qi H, Wang Q, Zhang M, Huang M, Xu Y, Hu S. Is ecstasy-induced protracted symptom of motion perception associated with altered regional homogeneity of brain? Chin Med J (Engl). 2014;127(17):3189-91. IF2014=1.053

 

Hu S, Xu D, Peterson BS, Wang Q, Lai J, Hu J, Wei N, Zhang M, Xu Y. Differing default mode network activities in men with homosexual or heterosexual preferences. J Sex Med. 2014;11(10):2474-84. IF2014=3.151

 

Liang C, Li H, Shen C, Lai J, Shi Z, Liu B, Tao HM. Genistein potentiates the anti-cancer effects of gemcitabine in human osteosarcoma via the downregulation of Akt and nuclear factor-κB pathway. Anticancer Agents Med Chem. 2012;12(5):554-63. IF2012=2.61

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