唐龙华  博士 /  副教授 / 博士生导师 

    2013年博士毕业于清华大学； 2013－2015，浙江大学光电科学与工程学院，特聘副研究员；2016至今，副教授，博士生导师。曾在美国伊利诺伊香槟分校、英国帝国理工学院访问交流。长期围绕生物分子光电测量技术与仪器开展研究工作，迄今以通讯或一作身份在Science Advances、Nature Communications、Nature Protocols等国际知名术期刊发表SCI论文40余篇；论文总被引10000余次，单篇最高他引1000+次（google scholar）。作为项目负责人主持国家自然科学基金、浙江省自然科学基金、国家重点研发计划等各类科研项目10余项；曾于2013年荣获教育部自然科学一等奖（4/7），2015年荣获国家自然科学二等奖（5/5），2021年获得浙江省杰出青年基金项目资助，2022年获得国家级青年人才项目资助。

      团队长期招聘硕士生、博士生、研究助理或博士后，欢迎不同学科背景人员加盟。2024级博士生和研究生尚有名额，欢迎联系咨询(lhtang@zju.edu.cn)。

Google Scholar: Citation: 11040, h-index: 40; i10-index: 59

https://scholar.google.com/citations?user=kqFbXp0AAAAJ&hl=en 

ISI Web of Science (Researcher ID: G-5412-2011): Citations: 9249; H-index: 38

http://www.researcherid.com/rid/G-5412-2011 

(updated on 2023-10-26 )

56 Ren Ren, Shenglin Cai, Xiaona Fang, Xiaoyi Wang, Zheng Zhang, Micol Damiani, Charlotte Hudlerova, Annachiara Rosa, Joshua Hope, Nicola Cook, Peter Gorelkin, Alexander Erofeev, Pavel Novak, Anjna Badhan, Michael Crone, Paul Freemont, Graham Taylor, Longhua Tang, Christopher Edwards, Andrew Shevchuk, Peter Cherepanov, Zhaofeng Luo, Weihong Tan, Yuri Korchev, and Aleksandar Ivanov, Joshua Edel

Multiplexed detection of viral antigen and RNA using nanopore sensing and encoded molecular probes

Nature Communications，2023, accepted

55. 沈逸;曾标峰;郑臻荣;唐龙华

隧道结纳米器件中的光电流调制与因素分析 Optical Modulation and Cause Analysis of Photocurrent in Nanoscale  Tunneling Junction Devices

中国激光 2023 ，50 （23 ）--

54. Yuxin Yang+, Tao Jiang+, Ye Tian, Biaofeng Zeng, Longhua Tang,*

Machine Learning-Aided Data Analysis in Single-Protein Conductance Measurement with Electron Tunneling Probes

 Chinese Journal of Chemistry  2023， DOI: 10.1002/cjoc.202300440

53. Bangrui Shao, Qiuxiang He, Tao Jiang, Biaofeng Zeng, Cuifang Kuang, Xu Liu, Longhua Tang *

Electrochemical Etching-Assisted Fabricating Quantum Tunneling Sensing Probes with Controlled Nanogap Width

Chemosensors, 2023 11(9), 480 

52. Tao Jiang+, Biaofeng Zeng+, Bintian Zhang, Longhua Tang,*

Single-Molecular Protein-based Bioelectronics via Electronic Transport: Fundamental, Devices and Applications 

Chemical Society Reviews, 2023， DOI: 10.1039/D2CS00519K

Single-molecular protein-based bioelectronics via electronic transport  fundamentals, devices and applications.pdf

前沿进展| 唐龙华等发表单分子蛋白质电子学领域《Nature Protocols》实验指南和《Chem Soc Rev》封面综述 

51. Tao Jiang, Xu Liu, Long Yi, Aleksandar P. Ivanov, Joshua B. Edel, and Longhua Tang*

Fabrication of electron tunnelling probes for measuring single protein conductance

Nature Protocols (Impact factor: 17.021), 2023， DOI: 10.1038/s41596-023-00846-3

Nature Protocols | 浙江大学唐龙华团队介绍了用于制造简单的、基于纳米管的隧道探针，适用于测量单蛋白电导 

50. Yuxuan Qiu, Cuifang Kuang, Xu Liu, Longhua Tang *

Single-molecule surface-enhanced Raman spectroscopy

Sensors, 2022，22(13), 4889;  DOI：10.3390/s22134889   

Single-Molecule Surface-Enhanced Raman Spectroscopy.pdf

49. Qiuxiang He and Longhua Tang*  

 Sub-5 nm nanogap electrodes towards single-molecular biosensing

Biosensors & Bioelectronics, 2022，213，114486,  DOI：10.1016/j.bios.2022.114486 

Sub-5 nm nanogap electrodes towards single-molecular biosensing（review）.pdf

48. Longhua Tang,*  Long Yi, Tao Jiang, Ren Ren, Binoy Paulose Nadappuram, Bintian Zhang,  Jian Wu, Xu Liu, Stuart Lindsay, Aleksandar P. Ivanov* Joshua B. Edel *

Measuring conductance switching in single proteins using quantum tunneling 

Science Advances, 2022，8(20), DOI: 10.1126/sciadv.abm8149 

sciadv.abm8149-Measuring conductance switching in single proteins using quantum tunneling.pdf

唐龙华课题组《Science Advances》发文报道基于量子隧穿的单分子蛋白质电导测量技术

浙江大学唐龙华等Sci. Adv.：利用隧穿结器件实现单分子蛋白质长时电导测量 

47.  Longhua Tang,* Binoy Paulose Nadappuram, Paolo Cadinu, Zhiyu Zhao, Liang Xue, Long Yi, Ren Ren, Jiangwei Wang,  Aleksandar P. Ivanov,* Joshua B. Edel*, 

Combined dielectrophoretic trapping and quantum tunnelling for molecular analysis at ultra-low analyte concentrations, 

Nature Communications, 2021, 12, 913  DOI：10.1038/s41467-021-21101-x

Tang 等 - 2021 - Combined quantum tunnelling and dielectrophoretic .pdf

浙江大学唐龙华等Nat. Commun.：结合介电泳捕获的量子隧穿传感技术实现超低浓度的单分子检测

46. Chang  Lu, Longhua Tang, Fei Gao, Yuzhi Li, Juewen Liu, JInkai Zheng*

 DNA-encoded Bimetallic Au-Pt Dumbbell Nanozyme for High-performance Detection and Eradication of Escherichia coli O157:H7

 Biosensors and Bioelectronics Pub Date : 2021-05-09, DOI: 10.1016/j.bios.2021.113327

45. Hui Zhao, Jinmei Yang, Yuxian Lu, Jinrui Dong, Longhua Tang*, Jiandong Feng *

 Modulated-light Induced Photocurrent Through the Liquid-Silicon-Liquid Interfaces

 Optik， 2021， https://doi.org/10.1016/j.ijleo.2021.167218

44. Yifan Zhang, Tingjie Song Tao Feng, Yilin Wan,  Nicholas T. Blum, Chengbo Liu, Chunqi Zheng,Tao Jiang, Qiang Li, Jing Lin, Longhua Tang, * Peng Huang, * 

Plasmonic Modulation of Gold Nanotheranostics for Targeted Photothermal-Augmented Immunotherapy in the Second NearInfrared Window, 

Nano Today, 2020 35, 100987 https://doi.org/10.1016/j.nantod.2020.100987 

DNA编程策略合成金纳米诊疗剂用于近红外二区的光热增强型癌症免疫治疗

43. Yifan Zhang, Yilin Wan，Yunyan Liao，Yanjie Hu，Tao Jiang, Ting He，Wei Bi，Jing Lin，Peng Gong，Longhua Tang*, and Peng Huang * 

Janus γ-Fe2O3/SiO2-based nanotheranostics for dual-modal imaging and enhanced synergistic cancer starvation/chemodynamic therapy, 

Science Bulletin  2020, 65(7), 564-572  https://doi.org/10.1016/j.scib.2019.12.024 

42. Xu Liu+, Yilin Wan+, Tao Jiang, Yifang Zhang, Peng Huang*, Longhua Tang* , 

Plasmon-Activated Nanozymes with Enhanced Catalytic Activity by Near-Infrared Light Irradiation,

 Chemical Communictions , 2020, 56, 1784.  doi:10.1039/C9CC08223A. Back cover

41. Tao Jiang，Pratibha Goel，Hui Zhao，Rui Ma，Linghua Zhu，Xiangjiang Liu，Longhua Tang* 

Internal Structure Tailoring in 3D Nanoplasmonic Metasurface for Surface‐Enhanced Raman Spectroscopy，

Particle & Particle Systems Characterization , 2020, 37,  1900345, DOI: 10.1002/ppsc.201900345 (Front Cover)

40. Hui Zhao+, Misha Liu,+ Tao Jiang, Jinjin Xu, Huirong Zhang, Chaofan Yu, Zipeng Liu, Ying Wang, Longhua Tang*

Ultrasensitive Monitoring of DNA Damage Associated with Free Radicals Exposure Using Dynamic Carbon Nanotubes Bridged Interdigitated Electrode Array

Environment International, 2020, 139 105672  

39. Renzhong Zhuang, Xueji Wang, Wenbo Ma, Yuhao Wu, Xu Chen, Longhua Tang, Haiming Zhu, Jiyong Liu, Lingling Wu, Wei Zhou, Xu Liu and Yang (Michael) Yang*, 

 Highly sensitive X-ray detector made of layered perovskite-like (NH4)3Bi2I9 single crystal with anisotropic response,

 Nature Photonics (IF: 31.583), 2019, 13, 602–608

38. Ye Ma, Debabrata Sikdar, Aleksandra Fedosyuk, Leonora Velleman, Minggang Zhao, Longhua Tang, Alexei A. Kornyshev*, Joshua B. Edel* 

Auxetic Thermoresponsive Nanoplasmonic Optical Switch 

ACS Applied Materials & Interfaces  2019, 11, 25, 22754-22760 

37. Wendao Xu, Lijuan Xie, Jianfei Zhu, Longhua Tang, Ranjan Singh, Chen Wang, Yungui Ma, Hou-Tong Chen, Yibin Ying 

Terahertz biosensing with a graphene-metamaterial heterostructure platform 

Carbon 2019, 247-252. DOI: 10.1016/j.carbon.2018.09.050 

36. Yiming Zhang, Tao Jiang,  Longhua  Tang* 

Near-Infrared Photoluminescence Biosensing Platform with Gold Nanorods-over-Gallium Arsenide Nanohorn Array 

Biosensors & Bioelectronics, 2017, 97, 278–284

35 . Longhua  Tang, Jinghong Li* 

Plasmon-based Colorimetric Nanosensors for Ultrasensitive Molecular Diagnostics,

ACS Sensors, 2017, 2, 857

34. Fang Yu, Yun Li, Mingyu Li,  Longhua  Tang*, Jian-Jun He,

 DNAzyme-integrated plasmonic nanosensor for bacterial sample-to-answer detection, 

Biosensors & Bioelectronics, 2017, 89, 880-885

33. Fang Yu, Yun Li, Mingyu Li,  Longhua  Tang, Jian-Jun He 

DNA Molecular Ruler-Modulated Photoluminescence Enhancement of Gallium Arsenide Modified with Plasmonic Nanoparticles 

Optik, 2016, 127 (23), 11492-11496

32. Dongyang Li,† Longhua  Tang,&#; Jingjing Wang, Xiangjiang Liu, Yibin Ying* 

Multidimensional SERS Barcodes on Flexible Patterned Plasmonic Metafilm for Anticounterfeiting Applications 

Advanced Optical Materials, 2016, 4,(10),1475-1480 

31. Xiangjiang Liu; Jiajun Wang,;  Longhua  Tang,  Lijuan Xie, Yibin Ying 

Flexible Plasmonic Metasurfaces with User-Designed Patterns for Molecular Sensing and Cryptography 

Advanced Functional Materials, 2016, 26(30), 5515–5523

30. Chang Lu, Xiangjiang Liu, Yunfeng Li, Fang Yu,  Longhua  Tang*, Yanjie Hu*, Yibing Ying* 

Multifunctional Janus hematite-silica nanoparticles: mimicking peroxidase-like activity and sensitive colorimetric detection of glucose

 ACS Applied Materials & Interface, 2015, 7, 15395-402

29. Xiangjiang Liu, Jingjing Wang, Jiajun Wang, Longhua  Tang*, Yibin Ying,

 Flexible and Transparent Surface-Enhanced Raman Scattering (SERS)-Active Metafilm for Visualizing Trace Molecules via Raman Spectral Mapping,

 Analytical Chemistry, 2016, 88(12): 6166-73

28．Xiangjiang Liu, Jianjun Wang, Longhua  Tang,* Yichen Wu, Tianren Fan, Yang Xu, Yibin Ying*,

Compact Shielding of Graphene Monolayer Leads to Extraordinary SERS-Active Substrate with Large-Area Uniformity and Long-Term Stability, 

Scientific Reports2015, 30; 5:17167.

27. Longhua  Tang, Ying Wang, and Jinghong Li*, 

The Graphene/Nucleic Acids- Nanobiointerface,

Chemical Society Reviews, 2015, 44(19), 6954-80

26. Jing Yan, Lida Wang,  Longhua  Tang, Lei Lin, and Jinghong Li*,

Enzyme-Guided Colorimetric

Biosensor Based on Dual-Functional Nanohybrid 

Biosensors & Bioelectronics, 2015, 70, 404-410

25. Xianxin Jiang, Yangqing Chen, Fang Yu,  Longhua  Tang, Mingyu Li, Jian-Jun He 

 High-Sensitivity Optical Biosensor Based on Cascaded Mach–Zehnder Interferometer and Ring Resonator Using Vernier Effect

Optics Letters 2014, 39 (22), 6363-6366 

24. Tingjie Song,  Longhua  Tang, Li Huey Tan, Xiaojing Wang, Nitya Sai Reddy Satyavolu, Hang Xing, Zidong Wang, Jinghong Li, Haojun Liang*, Yi Lu,* 

DNA-Encoded Tuning of Geometric and Plasmonic Properties of Nanoparticles Growing from Gold Nanorod Seeds 

 Angew. Chem. Int. Ed., 2014, 54, 8114-8118 

23. Xiangjiang Liu,  Longhua  Tang, Reinhard Niessner, Christoph Haisch and Yibin Ying 

Nitrite-Triggered Surface Plasmon-Assisted Catalytic Conversion of p-Aminothiop henol to p,p’-Dimercaptoazobenzene on Gold Nanoparticle: Surface-Enhanced Raman Scattering Investigation and Nitrite Sensing Application 

Anal. Chem., 2015, 87:499-506

22. Ying Wang,  Longhua  Tang, Zhaohui Li, Yuehe Lin, Jinghong Li* 

In Situ Simultaneous Monitoring of ATP and GTP Using a Graphene Oxide Nanosheet-Based Sensing Platform in Living Cells,

 Nature Protocols 2014, 9 (8), 1944-1955

21. Ruijie Deng,  Longhua  Tang, Qianqian Tian, Ying Wang, Lei Lin, Jinghong Li* 

Toehold-initiated Rolling Circle Amplification for Visualizing Individual MicroRNAs In Situ in Single Cells 

Angew. Chem. Int. Ed., 2014, 53, 2389-2393

20. Yangzhong Wang, Ke Qu,  Longhua  Tang, Zhaolong Li, Eric Moore, Xiangqun Zeng, Yang Liu*, Jinghong Li, 

Nanomaterials in Carbohydrate Biosensor, 

Trends in Analytical Chemistry, 2014, 58, 54-70

19.  Longhua  Tang, Dongyang, Li, Jinghong Li* 

Graphene Oxide.DNA Duplex-Based Logic Gate and Sensor Mediated by RecA-ssDNA Nucleoprotein Filaments 

Chem. Commun. 2013, 49, 9971-9973 

18.  Longhua  Tang, IkSu Chun, Zidong Wang, Jinghong Li*, Xiuling Li*, Yi Lu*, 

Plasmonic Enhanced Near-Infrared Photoluminescence of Gallium Arsenide for DNA Sensing,

Anal. Chem., 2013, 85, 9522-9527

Publisher Web Link | Open Access Link

17. Longhua  Tang, Haixing, Chang, Yang, Liu, and Jinghong Li* 

 Dupxle DNA.Graphene Oxide Biointerface: from Fundamental Understanding to Specific Enzymatic Effects 

Adv. Funct. Mater., 2012, 22, 3083–308 

16. Longhua  Tang, Yang, Liu, Md Monsur Ali, Dong Ku Kang, Weian Zhao*, and Jinghong Li*,

Colorimetric and Ultrasensitive Bioassay Based on a Dual-Amplification System Using Aptamer and DNAzyme,

 Anal. Chem., 2012, 84, 4711-4717

15. Zidong Wang, Longhua  Tang, Li Huey Tan, Jinghong Li, and Yi Lu* 

Discovery of DNA “Genetic Codes” for Abiological Metal Nanostructural Morphologies 

Angew. Chem. In. Ed., 2012, 51, 9078-9082 

14. Longhua  Tang, Ying Wang, Yang Liu, Jinghong Li* 

DNA-Directed Self-Assembly of Graphene Oxide for Ultrasensitive Oligonucleotide Assay, 

 ACS Nano,2011, 5, 3817–3822

13.  Longhua  Tang, Hongbing Feng, Jinsheng Cheng, Jinghong Li*, 

Uniform and Rich-Wrinkled Electrophoretic Deposited Graphene Film: A Robust Electrochemical Platform for TNT Sensing,

Chem. Commun., 2010, 46, 5882-5884 

12. Da Chen,  Longhua  Tang, Jinghong Li, 

Graphene-based materials in Electrochemistry,

Chem. Soc. Rev., 2010, 39, 3157-3180 

11. Haixin Chang, Longhua  Tang, Ying Wang, Jianhui Jiang*, Jinghong Li*, 

 Graphene Fluorescence Resonance Energy Transfer Aptasensor for the Thrombin Detection, 

Anal. Chem., 2010, 82, 2341–2346 

10. Jinsheng Cheng,  Longhua  Tang, Jingying Xu, 

An Economical, Green Pathway to Biaryls: Palladium Nanoparticles Catalyzed Ullmann Reaction in Ionic Liquid.Supercritical Carbon Dioxide  System, 

Adv. Synth. Cat., 2010, 352,3275–3286 

9. Qiong Zeng, Jinsheng Cheng,  Longhua  Tang, Xiaofei Liu, Yanzhe Liu, Jinghong Li*, Jianhui Jiang*, 

 Self-Assembled Graphene–Enzyme Hierarchical Nanostructures for Electrochemical Biosensing, 

Adv. Funct. Mater., 2010, 20, 3366–3372

8.  Longhua  Tang, Ying Wang, Yueming Li, Hongbing Feng, Jin Lu, Jinghong Li*, 

Preparation, Structure and Electrochemical Properties of Graphene Modified Electrode, 

Adv. Funct. Mater., 2009, 19, 2782-2789 

7. Yueming Li,  Longhua  Tang, Jinghong Li*, 

Pt-Graphene Nano Composites as the Anode Catalyst of Methanol Oxidation, 

 Electrochem. Commun., 2009, 11, 846-84 

6. Ying Wang, Jin Lu,  Longhua  Tang, Haixin Chang, Jinghong Li*, 

Graphene Oxide-Amplified Electrogenerated Chemiluminescence of Quantum Dots and its Selective Sensing, 

 Anal. Chem., 2009, 81, 9710–9715  

5. Ying Wang, Yueming Li,  Longhua  Tang, Jinghong Li*, 

Application of Graphene Modified Electrode for Selective Detection of Dopamine, 

 Elecrochem. Commun., 2009, 11, 889-892  

4. Longhua Tang, Yihua Zhu*, Xiaoling Yang, Chunzhong Li, 

Self-Assembled CNTs.CdS.Dehydrogenase Hybrid-Based Amperometric Biosensor Triggered by Photovoltaic Effect, 

Biosens. Bioelectron., 2008, 24, 319-323.  

3. Longhua  Tang, Yihua Zhu*, Xiaoling Yang, Chunzhong Li, 

An Enhanced Biosensor for Glutamate based on Self-Assembled Carbon Nanotubes and Dendrimer-Encapsulated Platinum Nanobiocomposites-Doped Polypyrrole Film, 

Anal. Chim. Acta., 2007, 597, 145-150 

2.  Longhua  Tang, Yihua Zhu*, Lihuan Xu, Chunzhong Li, 

 Amperometric Glutamate Biosensor Based on Self-assembling Glutamate Dehydrogenase and Dendrimer-Encapsulated Platinum Nanoparticles onto Carbon Nanotubes,

 Talanta, 2007, 73, 438-443

1.  Longhua  Tang, Yihua Zhu*, Lihuan Xu, Xiaoling Yang, Chunzhong Li,

 Properties of  Dendrimer-Encapsulated Pt Nanoparticles Doped Polypyrrole Composite Films and Their Electrocatalytic Activity for Glucose Oxidation,

 Electroanalysis, 2007, 19, 1677-1682

[11] 浙江大学. 基于纳米孔的 SARS-CoV-2 病毒检测方法:CN202311058930.8[P]. 2023-08-22.

申请人:浙江大学.

发明/设计人:唐龙华,江涛,任壬,蔡盛林

申请日期:2022-08-22

[10] 浙江大学. 基于纳米间隙针尖增强的单分子拉曼光谱系统:CN202211399078.6[P]. 2023-05-02.

申请人:浙江大学.

发明/设计人:唐龙华,邱宇轩,曾标峰,江涛,邵邦睿,匡翠方,刘旭.

申请日期:2022-11-09

公开/公告日:2023-05-02

[9] 浙江大学. 一种基于隧穿电极的生物分子检测方法:CN202211311286.6[P]. 2022-12-30.

申请人:浙江大学.

发明/设计人:唐龙华,江涛.

申请日期:2022-10-25

公开/公告日:2022-12-30

[8] 浙江大学. 一种形成纳米间隙电极对的制备方法:CN202110620000.1[P]. 2021-09-17.

申请人:浙江大学.

发明/设计人:唐龙华,江涛.

申请日期:2021-06-03

公开/公告日:2021-09-17

[7] 浙江大学. 基于纳米间隙电极对下的时域、空域和谱域单分子表征装置:CN202110600830.8[P]. 2021-10-22.

申请人:浙江大学.

发明/设计人:刘旭,唐龙华,刘少聪.

申请日期:2021-05-31

公开/公告日:2021-10-22

[6] 浙江大学. 一种集成纳米孔的分子隧穿检测装置:CN202110620031.7[P]. 2021-09-14.

申请人:浙江大学.

发明/设计人:唐龙华,江涛.

申请日期:2021-06-03

公开/公告日:2021-09-14

[5] 浙江大学. 一种基于两性纳米颗粒的高灵敏度SERS分子检测方法:CN201810916543.6[P]. 2020-07-03.

申请人:浙江大学.

发明/设计人:唐龙华,江涛,赵慧,刘旭.

申请日期:2018-08-13

公开/公告日:2020-07-03

[4] 浙江大学. 一种基于纳米颗粒光热转换效应的激光器热调谐结构:CN201820486946.7[P]. 2018-10-19.

申请人:浙江大学.

发明/设计人:唐龙华,赵慧,江涛,刘旭.

申请日期:2018-04-08

公开/公告日:2018-10-19

[3] 浙江大学. 三维立体叉指电极:CN201810307445.2[P]. 2018-08-07.

申请人:浙江大学.

发明/设计人:唐龙华,赵慧,江涛,刘旭.

申请日期:2018-04-08

公开/公告日:2018-08-07

[2] 浙江大学. 基于纳米颗粒光热转换效应的激光器热调谐方法:CN201810306697.3[P]. 2018-08-21.

申请人:浙江大学.

发明/设计人:唐龙华,赵慧,江涛,刘旭.

申请日期:2018-04-08

公开/公告日:2018-08-21

[1] 浙江大学. 一种新型三维立体叉指电极:CN201820487575.4[P]. 2018-11-27.

申请人:浙江大学.

发明/设计人:唐龙华,赵慧,江涛,刘旭.

申请日期:2018-04-08

公开/公告日:2018-11-27

1. 研究生必修课《科技写作》（秋学期）

2. 本科生大三/大四 《硅基光子学》（Silicon Photonics）， 秋学期