潘荣辉，江苏丹阳人。2018年入职浙江大学组建实验团队，主要围绕水稻、烟草、油菜等作物开展植物逆境发育和合成生物学相关的代谢和激素调控研究。近期研究成果发表于Nature、Developmental Cell、Plant Cell、Trends in Biotechnology、New Phytologist等领域内重要期刊，其中关于植物抗逆激素水杨酸合成机制解析的Nature论文是浙江大学作物学一级学科的首篇CNS正刊论文。入选国家高层次青年人才计划、农业农村部神农青年英才计划、唐仲英基金会“仲英青年学者”、浙江省高层次人才特殊支持计划青年拔尖人才、浙江省基金委杰出青年科学基金项目、浙江省“领军型创新团队”、浙江大学“双专计划”、浙江大学杭州国际科创中心“青年人才卓越计划”、浙江大学“优秀青年科研造峰计划A类”、浙江大学农业生命环境学部“优秀人才培育计划”等人才培养项目。荣获2025年中国植物生理与分子生物学学会卫志明青年创新奖。

教育背景

2009年9月-2014年12月，博士，生物化学和分子生物学专业，密歇根州立大学，美国

2005年9月-2009年7月，学士，生物化学专业，生命科学学院，南京大学

工作经历

2025年6月起，PI，研究员，水稻生物育种全国重点实验室，浙江大学

2021年10月起，PI，研究员，生物与分子智造研究院，浙江大学杭州国际科创中心

2018年3月起，PI，“百人计划”研究员、博士生导师，农业与生物技术学院，浙江大学

2015年1月至2018年2月，研究助理、博士后，密歇根州立大学-美国能源部植物研究实验室

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欢迎博士后和有志于科研的研究生加入本实验室！可邮件联系咨询。

（当前实验室已培养人员中包括教授1人、研究员2人，在实验室期间主持国自然青年C类科学基金5项、博新计划1项、博后引进计划1项、博士后特别资助1项、博士后面上资助6项）

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主要论文（Selected publications）：

2025

• Chen J#, Feng Y#, Zhang Y#, Gao J#, Ou J, Wu W, Li C, Song S, Tai L, Rifat MH, Akhter D, Hu J, Feng P*, Shen X*, Pan R* (2025). Structure-guided Discovery of Novel Protein Functions in Plants. The Plant Cell, in press. (中科院综合1区) 
  

• Wang Y#, Song S#, Zhang W#, Deng Q, Feng Y, Tao M, Kang M, Zhang Q, Yang L, Wang X, Zhu C, Wang X, Zhu W, Zhu Y, Cao P, Chen J, Pan J, Feng S, Chen X, Dai H, Song S, Yang J, Zhao T, Cao F, Tao Z, Shen X, Last R, Hu J, Yu J, Fan P*, Pan R* (2025). Deciphering phenylalanine-derived salicylic acid biosynthesis in plants. Nature, 645(8079):208-217. (中科院综合1区) (full)

         [Comment: J Hyun, H Yoo (2025), Missing steps uncovered in a pathway plants use to produce the defence molecule salicylic acid. Nature, 645(8079):48-50.]          

         [Comment: J Huang, RAL van der Hoorn (2025), The ancestral salicylic acid biosynthesis pathway in plants. Trends in Plant Science, doi: 10.1016/j.tplants.2025.08.004.]         

         [Comment: K Li, L Luo, H Chen, D Wang, F Liu, ZQ Fu (2025), Three key steps complete the biosynthesis of phenylalanine-derived salicylic acid in diverse plant species. Molecular Plant, 18(10), 1613-1615.]

         [Comment: L Tian, I Feussner (2025), Hidden route to salicylic acid has finally been uncovered. Plant Communications, 101496.]          

         [Comment: Y Li, J Luo (2025), Unraveling the central puzzle in salicylic acid biosynthesis from phenylalanine. Journal of Integrative Plant Biology, doi: 10.1111/jipb.70016.]

         [Comment: Q Hu, G Liu, Z Zhang (2025), Deciphering the Conserved Catalytic step of PAL-Driven Salicylic Acid Biosynthesis Pathway in Plants. Horticulture Research, uhaf255.]         

         [Comment: P Miao, JM Zhou (2025), Solving the puzzle of salicylic acid biosynthesis in plants. Journal of Genetics and Genomics, doi: 10.1016/j.jgg.2025.08.003.]

         [Comment: 朱孝波，王立印，陈学伟 (2025),  水杨酸介导的植物免疫反应: 从代谢, 感知到免疫激活. 植物学报, 60(5), 679-692.] 

• Wang Y, Miao H, Qiu J, Liu M, Jin G, Zhang W, Song S, Fan P, Xin X, Hu J, Li R*, Pan R* (2025). Species- and organ-specific contribution of peroxisomal cinnamate:CoA ligases to benzoic and salicylic acid biosynthesis and function in Arabidopsis and rice. The Plant Cell, 37(1):koae329. (中科院生物1区) (full)

2024

• Wang Y#, Jin G#, Song S#, Jin Y, Wang X, Yang S, Shen X, Gan Y, Wang Y, Li R, Liu J, Hu J, Pan R* (2024). A peroxisomal cinnamate:CoA ligase-dependent phytohormone metabolic cascade in submerged rice germination. Developmental Cell, 59(11), 1363-1378. (中科院生物1区) (full)

[Comment: Wright Z, Bartel B (2024). Hormonal control of underwater germination in rice. Developmental Cell, 59(11), 1361-1362.]

[Comment: He Y, Zhao J, Wang Z (2024). Rice seed germination priming by salicylic acid and the emerging role of phytohormones in anaerobic germination. Journal of Integrative Plant Biology, 66(8), 1537-1539.]

• Song S#, Ye C#, Jin Y, Dai H, Hu J, Lian J*, Pan R* (2024). Peroxisome-based Metabolic Engineering for Biomanufacturing and Agriculture. Trends in Biotechnology, 42(9), 1161-1176. (中科院工程技术1区) (full)

• Deng Q#, Hong X#, Xia Y#, Gong Z#, Dai H, Chen J, Feng Y, Zhang J, Xie X, Li N, Shen X, Hu J, Zhang Q*, Lang X*, Pan R* (2024). Comprehensive identification of plant Peroxisome Targeting Signal type 1 tripeptides. New Phytologist, 243(5), 1642-1650. (中科院生物1区) (full)

• Wu J#, Deng Q#, Qiu Y#, Liu C, Lin C, Ru Y, Sun Y, Lai J, Liu L, Shen X, Pan R*, Zhao Y* (2024). Post-transfer adaptation of HGT-acquired genes and contribution to guanine metabolic diversification in land plants. New Phytologist, 244(2), 694-707. (中科院生物1区) (full)

• Wang Y, Pan R*, Hu J* (2024).  Impact of acute heat stress on mitochondrial function, ultra-structure and cardiolipin distribution in Arabidopsis. aBiotech, 5, 362-367. (full) 

• Deng Q, Jiang H, Hu J, Pan R* (2024). Identification of Auxiliary Organellar Targeting Signals for Plant Peroxisomes Using Bioinformatic Analysis of Large Protein Sequence Datasets Followed by Experimental Validation. Methods in Molecular Biology, 2792, 265-275. (full)

• Tao M#, Chen J#, Cui C#, Xu Y#, Xu J, Shi Z, Yun J, Zhang J, Ou G, Liu C, Chen Y, Zhu Z, Pan R, Xu S, Chen X, Rokas A, Zhao Y, Wang S*, Huang J*, Shen X* (2024). Identification of a longevity gene through evolutionary rate covariation of insect mito-nuclear genomes. Nature Aging, 4(8), 1076-1088. 

• Li W, Liu J, Li Z, Ye R, Chen W, Huang Y, Yuan Y, Zhang Y, Hu H, Zheng P, Fang Z, Tao Z, Song S, Pan R, Zhang J, Tu J, Sheen J, Du Hao* (2024). Mitigating growth-stress tradeoffs via elevated TOR signaling in rice. Molecular Plant, 17(2), 240-257. 

2023

• Akhter D#, Zhang Y#, Hu J*, Pan R* (2023). Protein ubiquitination in plant peroxisomes. Journal of Integrative Plant Biology, 65(2):371-380. (中科院生物1区) (full)

• Feng Y#, Wang Y#, Lu H#, Li J, Akhter D, Liu F, Zhao T, Shen X, Li X, Whelan J, Zhang T, Hu J, Pan R* (2023). Assembly and phylogenomic analysis of cotton mitochondrial genomes provide insights into the history of cotton evolution. Crop Journal, 11(6): 1782-1792. (中科院农学1区) (full)

• Zhang Y#, Wang X#, Wang X, Wang Y, Liu J, Wang S, Li W, Jin Y, Akhter D, Chen J, Hu J, Pan R* (2023), Bioinformatic analysis of short-chain dehydrogenase/reductase proteins in plant peroxisomes. Frontiers in Plant Science, 14, 1180647. (full)

• Ma B, Lu C, Wang Y, Yu J, Zhao K, Xue R, Ren H, Lv X, Pan R, Zhang J, Zhu Y, Xu J (2023). A genomic catalogue of soil microbiomes boosts mining of biodiversity and genetic resources. Nature Communications, 14(1), 7318. 

• Zheng P#, Ge J#, Ji J, Zhong J, Chen H, Luo D, Li W, Bi B, Ma Y, Tong W, Han L, Ma S, Zhang Y, Wu J, Zhao Y, Pan R, Fan P, Lu M, Du H* (2023). Metabolic engineering and mechanical investigation of enhanced plant autoluminescence. Plant Biotechnology Journal, 21(8), 1671-1681. 

2022

• Deng Q#, Li H#, Feng Y#, Xu R, Li W, Zhu R, Akhter D, Shen X, Hu J*, Jiang H*, Pan R* (2022). Defining upstream enhancing and inhibiting sequence patterns for plant Peroxisome Targeting Signal type 1 using large-scale in silico and in vivo analyses. The Plant Journal, 111(2), 567-582. (中科院生物1区) (full) 

• Li Y#, Liu Z#, Liu C#, Shi Z, Pang L, Chen C, Chen Y, Pan R, Zhou W, Chen X, Rokas A*, Huang J*, Shen X* (2022). HGT is widespread in insects and contributes to male courtship in lepidopterans. Cell, 185 (16), 2975-2987. 
  

• Lin Y, Li P, Zhang Y, Akhter D, Pan R, Fu Z, Huang M, Li X, Feng Y* (2022). Unprecedented organelle genomic variations in morning glories reveal independent evolutionary scenarios of parasitic plants and the diversification of plant mitochondrial complexes. BMC biology, 20(1), 1-16.

2018-2020

• Pan R, Liu J, Wang S, Hu J* (2020) Peroxisomes: versatile organelles with diverse roles in plants, New Phytologist, 225 (4), 1410-1427. (中科院生物1区)

• Li Z., Liu H., Ding Z., Yan J., Yu H., Pan R., Hu J., Guan Y., Hua J. (2020) Low temperature enhances plant immunity via salicylic acid pathway genes that are repressed by ethylene. Plant Physiology, 182 (1), 626-639.

• Pan R*, Liu J, Hu J* (2019) Peroxisomes in plant reproduction and seed-related development. Journal of Integrative Plant Biology, 61 (7), 784-802. (中科院生物1区) (full) 

• Ma W., Guan X., Li J., Pan R., Wang L., Liu F., Ma H., Zhu S., Hu J., Ruan Y., Chen X., Zhang T.* (2019) Mitochondrial Small Heat Shock Protein Mediates Seed Germination via Thermal Sensing. Proceedings of the National Academy of Sciences, 116 (10), 4716-4721.

• He F., Gao C., Guo G., Liu J., Gao Y., Pan R., Guan Y.*, Hu J. (2019) Maize annexin genes ZmANN33 and ZmANN35 encode proteins that function in cell membrane recovery during seed germination. Journal of Experimental Botany, 70(4), 1183-1195.

• Pan R#, Reumann S#, Lisik P, Tietz S, Olsen L, Hu J* (2018). Proteome analysis of peroxisomes from dark-treated senescent Arabidopsis leaves. Journal of Integrative Plant Biology, 60(11), 1028-1050. (中科院生物1区)
  

• Pan R, Satkovich J, Chen C, Hu J* (2018). The E3 ubiquitin ligase SP1-Like 1 plays a positive role in peroxisome biogenesis in Arabidopsis. The Plant Journal, 94, 836-846. (中科院生物1区)

• Pan R,Hu J* (2018). The Arabidopsis E3 Ubiquitin Ligase SP1 Targets to Chloroplasts, Peroxisomes, and Mitochondria. Plant Physiology, 176(1), 480-482. (中科院生物1区)

• Pan R, Hu J* (2018). Proteome of plant peroxisomes. Subcellular Biochemistry, 89, 3-45.

• Desai M., Pan R., Hu J.* (2017). Arabidopsis Forkhead-Associated Domain Protein 3 negatively regulates peroxisome division. Journal of Integrative Plant Biology, 59(7), 454.

• Pan R, Satkovich J, Hu J* (2016). The E3 ubiquitin ligase SP1 regulates peroxisome biogenesis in Arabidopsis. Proceedings of the National Academy of Sciences, 113(46), E7307-E7316. (中科院综合1区)

• Pan R, Kaur N, Hu J* (2014). The Arabidopsis mitochondrial membrane-bound ubiquitin protease UBP27 contributes to mitochondrial morphogenesis. The Plant Journal, 78(6), 1047-1059. (中科院生物1区)

• Pan R, Jones AD, Hu J* (2014). Cardiolipin-mediated mitochondrial dynamics and stress response in Arabidopsis. The Plant Cell, 26(1), 391–409. (中科院生物1区)

       本课题组从事水稻、油菜等农业植物的细胞器和细胞代谢研究，通过综合利用转录组学、代谢组学、进化生物学、机器学习和基因编辑等技术，系统解析影响作物产量和环境适应性的关键化合物代谢和功能机制，进而设计优化作物的产量和抗逆等性状，或创制高价值植物合成底盘。

      细胞器是植物代谢的亚细胞载体。我们致力于解析植物重要化合物的代谢机制和重要细胞器的代谢功能。过氧化物酶体、叶绿体、线粒体等能量细胞器负责的光合-光呼吸超循环，是有机物和化学能的来源，也是作物高产抗逆和提质增效的能量基础。我们通过遗传学、生物信息学等技术，挖掘重要细胞器代谢网络未知元件和通路，为提高植物产量和抗性提供理论基础；同时开展农业植物的细胞器代谢工程研究，旨在提高作物产量、营养和抗性。

      过氧化物酶体是多功能代谢细胞器，在光呼吸、激素合成、能量代谢、活性氧代谢等方面发挥重要且复杂的作用，其代谢和生理功能远未被完全认识，尤其在单子叶禾本科作物中缺乏系统研究。我们通过蛋白组学和人工智能算法，挖掘过氧化物酶体的代谢网络，解析其在水稻种子发芽和幼苗建立、水稻的生物和非生物胁迫响应中的生理功能。

博士后（postdoc）：

朱仪方（南京农业大学/植生所）；宋书言（南京大学/入选博新计划）；王玉康（浙江大学）；台莉（西北农林大学）

研究生（graduate student）：

刘军；韩京京；邓倩文；王晓雯；金益君

朱霞；夏雨清；王欣瑜；陈佳荣；朱万欣；MH Rifat

（一）本科生课程：1. 种子学；2. 种子生物学；3. 学术英文写作。

（二）研究生课程：1. 作物科学研究理论与方法；2. 种子科学研究进展；3. 种子科学与技术。

左--->右：

王赛赛（硕士）；徐若楠（硕士）；Delara Akhter（博士后，现任锡尔赫特农业大学教授）；冯彦磊（博士后，现任浙大杭州国际科创中心研究员）；李未然（硕士）。

左--->右：

张钰婵（博士，现任上海市食品药品检验研究院博士后）。